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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-KDM4B (Thr305) Polyclonal Antibody

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货号 TMAB-10893

Anti-Phospho-KDM4B (Thr305) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-KDM4B (Thr305)。Anti-Phospho-KDM4B (Thr305) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-KDM4B (Thr305) Polyclonal Antibody

Anti-Phospho-KDM4B (Thr305) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10893

Anti-Phospho-KDM4B (Thr305) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-KDM4B (Thr305)。Anti-Phospho-KDM4B (Thr305) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-KDM4B (Thr305) Polyclonal Antibody is a Rabbit antibody targeting Phospho-KDM4B (Thr305). Anti-Phospho-KDM4B (Thr305) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Chromosome. Associates with euchromatic regions. Does not associate with heterochromatin.
组织特异性Expressed in all tissues examined, with high levels in fetal liver, thymus, lymph node, spleen and peripheral blood leukocytes and lower level in bone marrow.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Enables histone H3-methyl-lysine-36 demethylase activity and histone H3-methyl-lysine-9 demethylase activity. Involved in histone H3-K36 demethylation and histone H3-K9 demethylation. Located in cytosol and nucleoplasm. Implicated in autosomal dominant non-syndromic intellectual disability; breast cancer; colorectal cancer; malignant peripheral nerve sheath tumor; and stomach cancer. Biomarker of several diseases, including alopecia areata; lung cancer; medulloblastoma; prostate cancer; and stomach cancer. [provided by Alliance of Genome Resources, Apr 2022]
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human JMJD2B around the phosphorylation site of Thr305
抗原种属
Human
基因名称
KDM4B
基因ID
23030
蛋白名称
Lysine-specific demethylase 4B
Uniprot ID
O94953
功能
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
化学信息
分子量Theoretical: 122 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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