Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Moxipraquine 是一种新型的8-氨基喹诺酮类化合物,对克氏锥虫具有抗感染活性。Moxipraquine 能有效抑制寄生虫血症,但不能根除小鼠或豚鼠的感染。Moxipraquine 对重度利什曼原虫、墨西哥乳杆菌和巴西乳杆菌的实验性感染有效,但对巴西乳杆菌无效。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 1,130 | 现货 | ||
5 mg | ¥ 2,760 | 现货 | ||
10 mg | ¥ 3,970 | 现货 | ||
25 mg | ¥ 6,560 | 现货 | ||
50 mg | ¥ 8,930 | 现货 | ||
100 mg | ¥ 11,800 | 现货 | ||
500 mg | ¥ 23,900 | 现货 |
产品描述 | Moxipraquine is a novel 8-aminoquinolone compound with anti-infective activity against Trypanosoma cruzi. Moxipraquine effectively inhibited parasitemia but did not eradicate infections in mice or guinea pigs. Moxipraquine was effective against experimental infections of Leishmania major, Lactobacillus mexicanus, and Lactobacillus brasiliensis, but was Ineffective. |
体内活性 |
Moxipraquine (5, 15, or 45 mg base/kg; oral; 14 days) was effective in suppressing parasitemia but did not eradicate the infection from mice or guinea pigs.[1] Moxipraquine (50 mg base/kg; oral; 5 times) was effective on experimental infections of Leishmania major, L. Mexicana mexicana, and L.brasiliensis panamensis but not L.b.brasiliensis.[1] |
分子量 | 414.58 |
分子式 | C24H38N4O2 |
CAS No. | 23790-08-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 18.33 mg/mL (44.22 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.4121 mL | 12.0604 mL | 24.1208 mL | 60.302 mL |
5 mM | 0.4824 mL | 2.4121 mL | 4.8242 mL | 12.0604 mL | |
10 mM | 0.2412 mL | 1.206 mL | 2.4121 mL | 6.0302 mL | |
20 mM | 0.1206 mL | 0.603 mL | 1.206 mL | 3.0151 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Moxipraquine 23790-08-1 Microbiology/Virology Antibiotic Inhibitor inhibitor inhibit