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BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)
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货号 TMPJ-00325
别名 SKR5, Serine/Threonine-Protein Kinase Receptor R5, CD292, Bone Morphogenetic Protein Receptor Type-1A, BMPR-1A, BMPR1A, BMP Type-1A Receptor, ALK-3, ALK3, ACVRLK3, Activin Receptor-Like Kinase 3
Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, binding with ligands. Defects in BMPR1A are a cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2 (HMPS2).
其他形式的 “BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)”:
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)
一键复制产品信息 还可以SPR兼容缓冲液
货号 TMPJ-00325 别名 SKR5, Serine/Threonine-Protein Kinase Receptor R5, CD292, Bone Morphogenetic Protein Receptor Type-1A, BMPR-1A, BMPR1A, BMP Type-1A Receptor, ALK-3, ALK3, ACVRLK3, Activin Receptor-Like Kinase 3
Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, binding with ligands. Defects in BMPR1A are a cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2 (HMPS2).
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 243 | 6-8日内发货 | |
| 10 μg | ¥ 380 | 6-8日内发货 | |
| 20 μg | ¥ 596 | 5日内发货 | |
| 50 μg | ¥ 1,170 | 5日内发货 | |
| 100 μg | ¥ 2,130 | 5日内发货 | |
| 200 μg | ¥ 3,920 | 5日内发货 | |
| 500 μg | ¥ 8,860 | 5日内发货 | |
| 1 mg | ¥ 12,600 | 5日内发货 |
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| 产品描述 | Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, binding with ligands. Defects in BMPR1A are a cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2 (HMPS2). |
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| 研究背景 | Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, binding with ligands. Defects in BMPR1A are a cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2 (HMPS2). |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-hFc-6xHis |
| 蛋白编号 | P36894 |
| 氨基酸序列 | Gln24-Arg152 |
| 蛋白构建 | Gln24-Arg152 |
| 蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | SKR5, Serine/Threonine-Protein Kinase Receptor R5, CD292, Bone Morphogenetic Protein Receptor Type-1A, BMPR-1A, BMPR1A, BMP Type-1A Receptor, ALK-3, ALK3, ACVRLK3, Activin Receptor-Like Kinase 3 |
| 内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| 分子量 | 60 KDa (reducing condition) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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