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BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)

BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)

产品编号 TMPJ-00325
别名: BMP Type-1A Receptor, Bone Morphogenetic Protein Receptor Type-1A, BMPR-1A, ALK-3, Serine/Threonine-Protein Kinase Receptor R5, BMPR1A, ALK3, CD292, Activin Receptor-Like Kinase 3, SKR5, ACVRLK3

Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, binding with ligands. Defects in BMPR1A are a cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2 (HMPS2).

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BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)
规格 价格/CNY 货期 数量
10 μg ¥ 380 5日内发货
50 μg ¥ 1,170 5日内发货
500 μg ¥ 8,860 5日内发货
1 mg ¥ 12,600 5日内发货
夏季3重特惠
药物设计专题培训
Chloroquine限时半价
产品目录号及名称: BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His) (TMPJ-00325)
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产品描述 Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, binding with ligands. Defects in BMPR1A are a cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2 (HMPS2).
种属 Human
表达系统 HEK293 Cells
标签 C-hFc-6xHis
蛋白编号 P36894
别名 BMP Type-1A Receptor, Bone Morphogenetic Protein Receptor Type-1A, BMPR-1A, ALK-3, Serine/Threonine-Protein Kinase Receptor R5, BMPR1A, ALK3, CD292, Activin Receptor-Like Kinase 3, SKR5, ACVRLK3
氨基酸序列 Gln24-Arg152
蛋白构建 Gln24-Arg152
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 60 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, binding with ligands. Defects in BMPR1A are a cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2 (HMPS2).

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Keywords

BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His) ACVRLK 3 CD-292 ACVRLK-3 CD 292 BMP Type-1A Receptor Bone Morphogenetic Protein Receptor Type-1A SKR-5 SKR 5 BMPR-1A ALK-3 Serine/Threonine-Protein Kinase Receptor R5 ALK 3 BMPR1A ALK3 CD292 Activin Receptor-Like Kinase 3 SKR5 ACVRLK3 recombinant recombinant-proteins proteins protein

 

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