规格

价格

库存

数量

5 μg

¥ 495

现货

10 μg

¥ 790

现货

20 μg

¥ 1,330

3日内发货

50 μg

¥ 2,630

3日内发货

100 μg

¥ 4,460

现货

生物活性

产品描述	Peroxiredoxin 2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 24 kDa and the accession number is P32119.
生物活性	Measured by its ability to reduce H2O2. The specific activity is >300 pmoles/min/μg.
研究背景	Peroxiredoxin-2, also known as Natural killer cell-enhancing factor B, NKEF-B, Thiol-specific antioxidant protein, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, PRDX2 and NKEFB, is a cytoplasm protein that belongs to the ahpC / TSA family. Peroxiredoxin-2 / PRDX2 contains one thioredoxin domain. Peroxiredoxin-2 / PRDX2 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system. Peroxiredoxin-2 / PRDX2 is not able to receive electrons from glutaredoxin. It may play an important role in eliminating peroxides generated during metabolism. Peroxiredoxin-2 / PRDX2 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. The Peroxiredoxins / Prx are a family of peroxidases that can reduce H2O2 using an electron from thioredoxin (Trx) or other substances. The mammalian Peroxiredoxins / Prx family is divided into six groups (PRDX1，PRDX2, PRDX3, PRDX4, PRDX5, PRDX6) on the basis of homology of amino acid sequences. They are located in the cytosol and play a role in the cell signaling system. All six mammalian peroxiredoxins are expressed in the lung. Peroxiredoxins / Prx is overexpressed in breast cancer tissues to a great extent suggesting that Peroxiredoxins / Prx has a proliferative effect and may be related to cancer development or progression.
种属	Human
表达系统	Baculovirus Insect Cells
标签	N-His
蛋白编号	P32119
蛋白构建	A DNA sequence encoding the human PRDX2 (P32119) (Met 1-Asn 198) was expressed, with a polyhistidine tag at the N-terminus. Predicted N terminal: Met
蛋白纯度	> 92 % as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris, 100 mM NaCl, pH 8.0, 10% gly. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
别名	TSA, TPX1, TDPX1, PTX1, PRXII, PRX2, PRP, peroxiredoxin 2, NKEF-B, NKEFB, HEL-S-2a
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	24 kDa (predicted); 27 kDa (reducing conditions)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

Peroxiredoxin 2 Protein, Human, Recombinant (His)

Peroxiredoxin 2 Protein, Human, Recombinant (His)

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