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顶部生物活性储存和溶解信息计算器

Anti-Endothelin B Receptor Antibody (9N820)

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Anti-Endothelin B Receptor Antibody (9N820)
产品编号 TMAC-01292
别名 WS4A, HSCR2, HSCR, ETRB, ET-BR, ETBR, ET-B, ETB, endothelin receptor type B, ABCDS

Anti-Endothelin B Receptor Antibody (9N820) 是一种 Rabbit 抗体，靶向 Endothelin B Receptor。Anti-Endothelin B Receptor Antibody (9N820) 可用于 WB,IP。

Anti-Endothelin B Receptor Antibody (9N820)

Anti-Endothelin B Receptor Antibody (9N820)

Rating icon 还可以
Anti-Endothelin B Receptor Antibody (9N820)
产品编号 TMAC-01292 别名 WS4A, HSCR2, HSCR, ETRB, ET-BR, ETBR, ET-B, ETB, endothelin receptor type B, ABCDS

Anti-Endothelin B Receptor Antibody (9N820) 是一种 Rabbit 抗体，靶向 Endothelin B Receptor。Anti-Endothelin B Receptor Antibody (9N820) 可用于 WB,IP。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-Endothelin B Receptor Antibody (9N820) is a Rabbit antibody targeting Endothelin B Receptor. Anti-Endothelin B Receptor Antibody (9N820) can be used in WB,IP.
别名WS4A, HSCR2, HSCR, ETRB, ET-BR, ETBR, ET-B, ETB, endothelin receptor type B, ABCDS
Ig Type
IgG
交叉反应
Human,zebrafish
验证活性
1. Western blot analysis of Endothelin B Receptor on different cells lysates using anti-Endothelin B Receptor antibody at 1/500 dilution. Positive control: Lane 1: Zebrafish, Lane 2: Raji, Line 3: JAR.
应用
WB
IP
推荐剂量
WB: 1:500-2000; IP: 1:10-50
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Endothelin receptor B (ETBR), also known as EDNRB, ETB, ETRB, HSCR and HSCR2, is a member of the guanine-binding, regulatory protein-coupled receptor family. Three isoforms of ETBR exist called isoform 1, isoform 2 and δ 3. ETBR is involved in the regulation of sodium excretion and glomular filtration rate (GFR). ETBR plays a role in the normal development of the neural crestderived cell lineages, epidermal melanocytes and enteric neurons. ETBR is expressed in lung, kidney, placenta, skeletal muscle and stem villi vessels. Both of the ET receptors, ETAR and ETBR, are activated by ET1, which results in inhibition of active lens sodium-potassium transport. Activation of the ET receptors also causes an increase in cytoplasmic calcium concentration in cultured lens epithelial cells. ETBR deficiency causes early onset dysfunction of the kidney, characterized by reduced sodium excretion, decreased GFR and slightly elevated blood pressure. Mutations in the gene encoding ETBR produce congenital aganglionic megacolon and pigment abnormalities. The multigenic disorder, Hirschsprung??s disease type 2, is also due to a mutation in the ETBR gene.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P24530
化学信息
分子量Theoretical: 50 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

HSCR-2HSCR 2

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