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Anti-Integrin alpha 5 Antibody (8Y946)

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货号 TMAB-07742

Anti-Integrin alpha 5 Antibody (8Y946) 是一种 Rabbit 抗体，靶向 Integrin alpha 5。Anti-Integrin alpha 5 Antibody (8Y946) 可用于 WB,IHC-P,IHC-Fr,IF,IP。

Anti-Integrin alpha 5 Antibody (8Y946)

Anti-Integrin alpha 5 Antibody (8Y946)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07742

Anti-Integrin alpha 5 Antibody (8Y946) 是一种 Rabbit 抗体，靶向 Integrin alpha 5。Anti-Integrin alpha 5 Antibody (8Y946) 可用于 WB,IHC-P,IHC-Fr,IF,IP。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Integrin alpha 5 Antibody (8Y946) is a Rabbit antibody targeting Integrin alpha 5. Anti-Integrin alpha 5 Antibody (8Y946) can be used in WB,IHC-P,IHC-Fr,IF,IP.
Ig Type
IgG
克隆号
8Y946
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIFIP
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; IP: 1:20-50
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1.
抗原信息
免疫原
A synthesized peptide: human Integrin alpha 5
抗原种属
Human
基因名称
ITGA5
基因ID
3678
蛋白名称
Integrin alpha-5
Uniprot ID
P08648
功能
CD49e is the integrin alpha 5 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 5 undergoes post translational cleavage in the extracellular domain to yield disulfide linked light and heavy chains that join with beta 1 to form a fibronectin receptor that is known variously: in lymphocytes as very late (activation) antigen 5 (VLA5); in platelets as glycoprotein IcIIa; and in fibroblasts as extracellular matrix receptor 6 (ECMVI). In addition to adhesion, integrins are known to participate in cell surface mediated signalling.
化学信息
分子量Theoretical: 115 kDa. Actual: 150 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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