The human astrocytoma cell line U373 MG was incubated with 0.1-100 µM tenidap for 30 min and then stimulated with 50 µM C6-ceramide for 24 h. Tenidap inhibited the dose-dependent ceramide-induced IL-6 protein synthesis in U373 human astrocytoma cells.[4]

雄性Wistar大鼠在三氯司他汀诱导的持续性癫痫（SE）后，每天10毫克/公斤的剂量给药10天，Tenidap-SE组存活46.88±10.70个神经元，Tenidap-SE组存活37.75±8.78个神经元，Tenidap显著抑制了COX-2在海马尤其是CA3区的表达[3]。