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顶部生物活性储存和溶解信息计算器

Anti-XPO1 Antibody (2H608)

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Anti-XPO1 Antibody (2H608)
产品编号 TMAC-00982
别名 XPO 1, Exportin-1, Exp1, CRM1, Chromosome region maintenance 1 protein homolog

Anti-XPO1 Antibody (2H608) 是一种 Rabbit 抗体，靶向 XPO1。Anti-XPO1 Antibody (2H608) 可用于 WB,ICC,IF,IHC,FCM。

Anti-XPO1 Antibody (2H608)

Anti-XPO1 Antibody (2H608)

Rating icon 还可以
Anti-XPO1 Antibody (2H608)
产品编号 TMAC-00982 别名 XPO 1, Exportin-1, Exp1, CRM1, Chromosome region maintenance 1 protein homolog

Anti-XPO1 Antibody (2H608) 是一种 Rabbit 抗体，靶向 XPO1。Anti-XPO1 Antibody (2H608) 可用于 WB,ICC,IF,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-XPO1 Antibody (2H608) is a Rabbit antibody targeting XPO1. Anti-XPO1 Antibody (2H608) can be used in WB,ICC,IF,IHC,FCM.
别名XPO 1, Exportin-1, Exp1, CRM1, Chromosome region maintenance 1 protein homolog
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of CRM1 on 293T and Hela cell lysates using anti-CRM1 antibody at 1/500 dilution.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CRM1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-CRM1 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue using anti-CRM1 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded rat skeletal muscle tissue using anti-CRM1 antibody. Counter stained with hematoxylin.
6. ICC staining CRM1 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. ICC staining CRM1 in SiHa cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. ICC staining CRM1 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
9. Flow cytometric analysis of K562 cells with CRM1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
WB
ICC
IF
IHC
FCM
推荐剂量
WB: 1:500; IHC: 1:50-100; ICC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Protein transport across the nucleus is a selective, multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Two cytosolic factors centrally involved in the recognition and docking process are the karyopherin alpha1 and karyopherin beta1 subunits. p62 glycoprotein is a nucleoporin that is not only involved in the nuclear import of proteins, but also the export of nascent mRNA strands. NTF2 (nuclear transport factor 2) interacts with nucleoporin p62 as a homodimer composed of two monomers, and may be an obligate component of functional p62. CRM1 has been shown to be an export receptor for leucine-rich proteins that contain the nuclear export signal (NES).
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: within C terminal human CRM1
抗原种属
human
Uniprot ID
O14980
化学信息
分子量Theoretical: 123 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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