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Anti-Phospho-IRS-1 (Ser639) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-IRS-1 (Ser639)。Anti-Phospho-IRS-1 (Ser639) Polyclonal Antibody 可用于 WB,IHC。
Anti-Phospho-IRS-1 (Ser639) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-IRS-1 (Ser639)。Anti-Phospho-IRS-1 (Ser639) Polyclonal Antibody 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,230 | 5日内发货 |
产品描述 | Anti-Phospho-IRS-1 (Ser639) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IRS-1 (Ser639). Anti-Phospho-IRS-1 (Ser639) Polyclonal Antibody can be used in WB,IHC. |
别名 | p-IRS1 (Ser639), p-IRS1 (S639), IRS1 (p-Ser639), IRS1 (p-S639), IRS-1, Insulin receptor substrate 1 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of extracts from 293 cells untreated or treated with serum using IRS-1 (Phospho-Ser639) Antibody TMAC-02244. 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IRS-1 (Phospho-Ser639) Antibody TMAC-02244 (left) or the same antibody preincubated with blocking peptide (right). |
应用 | |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of serine 639 (P-K-S(p)-V-S) derived from Human IRS-1 |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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