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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GABRA1 Polyclonal Antibody 2

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货号 TMAB-06255

Anti-GABRA1 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 GABRA1。Anti-GABRA1 Polyclonal Antibody 2 可用于 WB。

Anti-GABRA1 Polyclonal Antibody 2

Anti-GABRA1 Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-06255

Anti-GABRA1 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 GABRA1。Anti-GABRA1 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

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产品描述
Anti-GABRA1 Polyclonal Antibody 2 is a Rabbit antibody targeting GABRA1. Anti-GABRA1 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Rat,Mouse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
组织特异性Highly expressed in brain and weakly in heart, small intestine and uterus. Isoform 1A is mostly expressed in granular cell and molecular layer. Isoform 1B is mostly expressed in Purkinje cells. Isoform 1E is predominantly expressed in peripheral tissues as kidney, lung, trachea, colon, small intestine, stomach, bone marrow, thymus and mammary gland.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (g-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R alpha 1-6, GABAA R beta 1-3, GABAA R©1-3, GABAA R∂, GABAA R gamma, GABAA R delta 1 and GABAA R delta 2. The GABAB family is composed of GABAB R1 alpha and GABAB R1 beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2 and -3). The GABA transporters function to terminate GABA action.
抗原信息
免疫原
Recombinant Protein: human GABRA1 protein
抗原种属
Human
基因名称
GABRA1
基因ID
2554
蛋白名称
gamma-aminobutyric acid receptor subunit alpha-1
Uniprot ID
P14867
功能
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
化学信息
分子量Theoretical: 52 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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