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Anti-RANK/TNFRSF11A Antibody (8X52)
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产品编号 TMAY-02813
别名 tumor necrosis factor receptor superfamily member 11a, TRANCER, TNFRSF11A, RANK, PDB2, OSTS, OPTB7, OFE, ODFR, LOH18CR1, FEO, CD265
Anti-RANK/TNFRSF11A Antibody (8X52) 是一种 Rabbit 抗体，靶向 RANK/TNFRSF11A。Anti-RANK/TNFRSF11A Antibody (8X52) 可用于 ELISA。
Anti-RANK/TNFRSF11A Antibody (8X52)
Anti-RANK/TNFRSF11A Antibody (8X52)
还可以产品编号 TMAY-02813 别名 tumor necrosis factor receptor superfamily member 11a, TRANCER, TNFRSF11A, RANK, PDB2, OSTS, OPTB7, OFE, ODFR, LOH18CR1, FEO, CD265
Anti-RANK/TNFRSF11A Antibody (8X52) 是一种 Rabbit 抗体，靶向 RANK/TNFRSF11A。Anti-RANK/TNFRSF11A Antibody (8X52) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,279 | 5日内发货 |
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-RANK/TNFRSF11A Antibody (8X52) is a Rabbit antibody targeting RANK/TNFRSF11A. Anti-RANK/TNFRSF11A Antibody (8X52) can be used in ELISA. |
| 别名 | tumor necrosis factor receptor superfamily member 11a, TRANCER, TNFRSF11A, RANK, PDB2, OSTS, OPTB7, OFE, ODFR, LOH18CR1, FEO, CD265 |
| Ig Type | Rabbit IgG |
| 克隆号 | 8X52 |
| 交叉反应 | Human |
| 应用 | |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human TNFRSF11A (rh TNFRSF11A; TMPY-04157; NP_001257879.1; Met1-Pro212). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. It is an essential mediator for osteoclast and lymph node development. TNFRSF11A and its ligand are important regulators of the interaction between T cells and dendritic cells. It can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. Defects in TNFRSF11A can cause familial expansile osteolysis (FEO). FEO is a rare autosomal dominant bone disorder characterized by focal areas of increased bone remodeling. Defects in TNFRSF11A also can cause Paget disease of bone type 2 (PDB2). PDB2 is a bone-remodeling disorder with clinical similarities to FEO. Defects in TNFRSF11A are the cause of osteopetrosis autosomal recessive type 7 which characterized by abnormally dense bone, due to defective resorption of immature bone. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human TNFRSF11A Protein (TMPY-04157) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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