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Anti-C1D Antibody (6K759)

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产品编号 TMAY-02345

Anti-C1D Antibody (6K759) 是一种 Mouse 抗体,靶向 C1D。Anti-C1D Antibody (6K759) 可用于 ELISA。

Anti-C1D Antibody (6K759)

Anti-C1D Antibody (6K759)

Rating icon 还可以
产品编号 TMAY-02345

Anti-C1D Antibody (6K759) 是一种 Mouse 抗体,靶向 C1D。Anti-C1D Antibody (6K759) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-C1D Antibody (6K759) is a Mouse antibody targeting C1D. Anti-C1D Antibody (6K759) can be used in ELISA.
Ig Type
Monoclonal Mouse IgG1
克隆号
6K759
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human C1D (rh C1D; TMPY-02883; Q13901; Met1-Ser141). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景C1D nuclear receptor corepressor belongs to the C1D family. It is a DNA binding and apoptosis-inducing protein.C1D nuclear receptor corepressorinteracts with TSNAX and DNA-PKcs. It acts as a corepressor for the thyroid hormone receptor. It is thought that C1D nuclear receptor corepressor regulates TRAX/Translin complex formation. It is expressed in kidney, heart, brain, spleen, lung, testis, liver and small intestine. It plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. It potentiates transcriptional repression by NR1D1 and THRB. C1D nuclear receptor corepressorcan activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. It also can induce apoptosis in a p53/TP53 dependent manner.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human C1D protein (TMPY-02883)
抗原种属
Human
研究领域
Apoptosis Transcription Factors and Regulators
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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