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Anti-FZD1/Frizzled 1 Antibody (4X478)
还可以产品编号 TMAY-03097
Anti-FZD1/Frizzled 1 Antibody (4X478) 是一种 Rabbit 抗体，靶向 FZD1/Frizzled 1。Anti-FZD1/Frizzled 1 Antibody (4X478) 可用于 ELISA。
Anti-FZD1/Frizzled 1 Antibody (4X478)
Anti-FZD1/Frizzled 1 Antibody (4X478)
还可以产品编号 TMAY-03097
Anti-FZD1/Frizzled 1 Antibody (4X478) 是一种 Rabbit 抗体，靶向 FZD1/Frizzled 1。Anti-FZD1/Frizzled 1 Antibody (4X478) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-FZD1/Frizzled 1 Antibody (4X478) is a Rabbit antibody targeting FZD1/Frizzled 1. Anti-FZD1/Frizzled 1 Antibody (4X478) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4X478 |
| 交叉反应 | Mouse |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Frizzled-1 / FZD1 (TMPY-01165; NP_067432.2; Met1-His248). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Frizzled-1, also known as FZD1, belongs to theG-protein coupled receptor Fz/Smo family. FZD1 contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. FZD1 is expressed in adult heart, placenta, lung, kidney, pancreas, prostate, and ovary and in fetal lung and kidney. Frizzled is a family of G protein-coupled receptor proteins that serve as receptors in the Wnt signaling pathway and other signaling pathways. When activated, Frizzled leads to activation of Dishevelled in the cytosol. Frizzled proteins and the genes encoding them have been identified in an array of animals, from sponges to humans. Frizzled proteins play key roles in governing cell polarity, embryonic development, formation of neural synapses, cell proliferation, and many other processes in developing and adult organisms. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse Frizzled-1 / FZD1 protein (TMPY-01165) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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