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Anti-Ficolin 1/FCN1 Antibody (5G600)
还可以产品编号 TMAY-01346
Anti-Ficolin 1/FCN1 Antibody (5G600) 是一种 Rabbit 抗体，靶向 Ficolin 1/FCN1。Anti-Ficolin 1/FCN1 Antibody (5G600) 可用于 IHC-P。
Anti-Ficolin 1/FCN1 Antibody (5G600)
Anti-Ficolin 1/FCN1 Antibody (5G600)
还可以产品编号 TMAY-01346
Anti-Ficolin 1/FCN1 Antibody (5G600) 是一种 Rabbit 抗体，靶向 Ficolin 1/FCN1。Anti-Ficolin 1/FCN1 Antibody (5G600) 可用于 IHC-P。
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| 产品描述 | Anti-Ficolin 1/FCN1 Antibody (5G600) is a Rabbit antibody targeting Ficolin 1/FCN1. Anti-Ficolin 1/FCN1 Antibody (5G600) can be used in IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 5G600 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human FCN1 in human spleen (from 2 donors) with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to peripheral blood leukocytes. 2. Immunochemical staining of human FCN1 in human placenta with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to peripheral blood leukocytes. |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:100-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human FCN1 (rh FCN1; TMPY-01028; NP_001994.2; Met1-Ala326). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. The Ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. Three Ficolins have been identified in humans: L-Ficolin, H-Ficolin and M-Ficolin (also referred to as Ficolin-2, -3 and -1, respectively). They are soluble oligomeric defence proteins with lectin-like activity and they are structurally similar to the human collectins, mannan-binding lectin (MBL) and surfactant protein A and D. Dysfunction or abnormal expressions of Ficolins may involved in the pathogenesis of human diseases including infectious and inflammatory diseases, autoimmune disease and clinical syndrome of preeclampsia. They are soluble oligomeric defence proteins with lectin-like activity and they are structurally similar to the human collectins, mannan-binding lectin (MBL) and surfactant protein A and D. Upon recognition of the infectious agent, the Ficolins act through two distinct routes: initiate the lectin pathway of complement activation through attached serine proteases (MASPs), and a primitive opsonophagocytosis thus limiting the infection and concurrently orchestrating the subsequent adaptive clonal immune response. Ficolin-1 (FCN1) is predominantly expressed in the peripheral blood leukocytes. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human FCN1 protein (TMPY-01028) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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