NDRG1 gene is a member of the N-Myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Mutations in the NDRG1 gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. NDRG1 is a stress-responsive protein involved in hormone responses, cell growth, and differentiation. It acts as a tumor suppressor in many cell types.
生物活性 | Testing in progress |
产品描述 | NDRG1 gene is a member of the N-Myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Mutations in the NDRG1 gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. NDRG1 is a stress-responsive protein involved in hormone responses, cell growth, and differentiation. It acts as a tumor suppressor in many cell types. |
种属 | Human |
表达系统 | E. coli |
标签 | C-His |
蛋白编号 | Q92597 |
别名 | TARG1, PROXY1, RIT42, NDR1, DRG1, RTP, TDD5, CMT4D, CAP43, NMSL, N-myc downstream regulated 1, HMSNL, GC4, DRG-1 |
蛋白构建 | The Human NDRG1 (Q92597) (Met1-Cys394) was expressed with a polyhistidine tag at the C-terminus. |
蛋白纯度 | > 85 % as determined by SDS-PAGE |
分子量 | 43.8 kDa (predicted) |
内毒素 | Please contact us for more information. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | NDRG1 gene is a member of the N-Myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Mutations in the NDRG1 gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. NDRG1 is a stress-responsive protein involved in hormone responses, cell growth, and differentiation. It acts as a tumor suppressor in many cell types. |
bottom
您可能有的问题的答案可以在重组蛋白操作手册中找到
NDRG1 Protein, Human, Recombinant (His) RIT 42 TARG1 GC 4 GC-4 TDD-5 CAP-43 PROXY1 PROXY 1 RIT42 NDR1 DRG1 RTP TDD5 TARG-1 NDR 1 NDR-1 CMT4D TARG 1 TDD 5 CAP43 NMSL N-myc downstream regulated 1 DRG 1 RIT-42 CAP 43 PROXY-1 HMSNL GC4 DRG-1 recombinant recombinant-proteins proteins protein