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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ILP2 Polyclonal Antibody

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货号 TMAB-07685

Anti-ILP2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ILP2。Anti-ILP2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-ILP2 Polyclonal Antibody

Anti-ILP2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-07685

Anti-ILP2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ILP2。Anti-ILP2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-ILP2 Polyclonal Antibody is a Rabbit antibody targeting ILP2. Anti-ILP2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm (Probable).
组织特异性Testis specific in normal tissues.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Protects against apoptosis mediated by BAX.Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2 (1). ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues (1). ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ILP2
抗原种属
Human
基因名称
BIRC8
基因ID
112401
蛋白名称
Baculoviral IAP repeat-containing protein 8
Uniprot ID
Q96P09
功能
Protects against apoptosis mediated by BAX.
化学信息
分子量Theoretical: 26 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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