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Anti-Her2/ERBB2 Antibody-FITC (5S123)

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Anti-Her2/ERBB2 Antibody-FITC (5S123)
产品编号 TMAY-00035F
别名 erb-b2 receptor tyrosine kinase 2, EGFR2

Anti-Her2/ERBB2 Antibody-FITC (5S123) 是一种 FITC-conjugated Mouse 抗体，靶向 Her2/ERBB2。Anti-Her2/ERBB2 Antibody-FITC (5S123) 可用于 FCM。

Anti-Her2/ERBB2 Antibody-FITC (5S123)
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Anti-Her2/ERBB2 Antibody-FITC (5S123)

Rating icon 还可以
Anti-Her2/ERBB2 Antibody-FITC (5S123)
产品编号 TMAY-00035F 别名 erb-b2 receptor tyrosine kinase 2, EGFR2

Anti-Her2/ERBB2 Antibody-FITC (5S123) 是一种 FITC-conjugated Mouse 抗体，靶向 Her2/ERBB2。Anti-Her2/ERBB2 Antibody-FITC (5S123) 可用于 FCM。

规格价格库存数量
25 T
¥ 680
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100 T
¥ 1,495
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产品介绍

生物活性
产品描述
Anti-Her2/ERBB2 Antibody-FITC (5S123) is a FITC-conjugated Mouse antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody-FITC (5S123) can be used in FCM.
别名erb-b2 receptor tyrosine kinase 2, EGFR2
Ig Type
Mouse IgG1
克隆号
5S123
交叉反应
Human
验证活性
Flow cytometric analysis of Human Her2/ERBB2 expression on SKBR3. Cells were stained with FITC-conjugated anti-Human Her2/ERBB2. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This product is a recombinant monoclonal antibody expressed from HEK293 cells and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
FITC
其他可选修饰符
Unconjugated/APC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Human HER2 / ErbB2 protein (TMPY-01137)
抗原种属
Human
研究领域
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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4个月前
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