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顶部生物活性储存和溶解信息计算器

Anti-XDH Antibody (4C20)

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Anti-XDH Antibody (4C20)
产品编号 TMAC-04294
别名 XOR, XO, XDHA, XD, Xanthine oxidoreductase, Xanthine oxidase, Xanthine dehydrogenase/oxidase, Xanthine dehydrogenase, EC 1.17.3.2, EC 1.17.1.4

Anti-XDH Antibody (4C20) 是一种 Mouse 抗体，靶向 XDH。Anti-XDH Antibody (4C20) 可用于 IHC,FCM。

Anti-XDH Antibody (4C20)

Anti-XDH Antibody (4C20)

Rating icon 还可以
Anti-XDH Antibody (4C20)
产品编号 TMAC-04294 别名 XOR, XO, XDHA, XD, Xanthine oxidoreductase, Xanthine oxidase, Xanthine dehydrogenase/oxidase, Xanthine dehydrogenase, EC 1.17.3.2, EC 1.17.1.4

Anti-XDH Antibody (4C20) 是一种 Mouse 抗体，靶向 XDH。Anti-XDH Antibody (4C20) 可用于 IHC,FCM。

规格价格库存数量
50 μL
¥ 1,990
5日内发货
100 μL
¥ 2,980
5日内发货
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产品介绍

生物活性
产品描述
Anti-XDH Antibody (4C20) is a Mouse antibody targeting XDH. Anti-XDH Antibody (4C20) can be used in IHC,FCM.
别名XOR, XO, XDHA, XD, Xanthine oxidoreductase, Xanthine oxidase, Xanthine dehydrogenase/oxidase, Xanthine dehydrogenase, EC 1.17.3.2, EC 1.17.1.4
交叉反应
Human
验证活性
1. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-xanthine dehydrogenase antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-xanthine dehydrogenase antibody. Counter stained with hematoxylin.
3. Flow cytometric analysis of LOVO cells with xanthine dehydrogenase antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti mouse IgG was used as the secondary antibody.
应用
IHC
FCM
推荐剂量
IHC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProG affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The process of metabolizing purines to a common molecule known as xanthine is an essential process for the proper shuttling of uric acid. Xanthine oxidase is a flavoprotein enzyme that coordinates molybdenum and utilizes NAD+ as an electron acceptor to catalyze the oxidation of hypoxanthine to xanthine and then to uric acid. The predominant form of this enzyme is xanthine dehydrogenase, which is a homodimer that can be converted to xanthine oxidase by sulfhydryl oxidation or proteolytic modification. Xanthine oxidase is present in species ranging from bacteria to human and is ubiquitously expressed in mammalian tissues. In the oxidase form, this enzyme is coupled to the generation of free radicals. Individuals showing marked elevation of serum xanthine oxidase is suggestive of chronic liver disease and cholestasis, which is a condition defined by hepatic obstruction. Hepatic obstruction causes bile salts, the bile pigment bilirubin, and fats to accumulate in the blood stream instead of being eliminated normally. The clinical consequences of defects in xanthine oxidase range from mild to severe and even contribute to fatal disorders.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Peptide
Uniprot ID
P47989
化学信息
分子量Theoretical: 146 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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