购物车
- 全部删除
您的购物车当前为空
Anti-Cathepsin Z Antibody (3J329)
还可以产品编号 TMAY-03094
Anti-Cathepsin Z Antibody (3J329) 是一种 Rabbit 抗体，靶向 Cathepsin Z。Anti-Cathepsin Z Antibody (3J329) 可用于 ELISA,ICC/IF。
Anti-Cathepsin Z Antibody (3J329)
Anti-Cathepsin Z Antibody (3J329)
还可以产品编号 TMAY-03094
Anti-Cathepsin Z Antibody (3J329) 是一种 Rabbit 抗体，靶向 Cathepsin Z。Anti-Cathepsin Z Antibody (3J329) 可用于 ELISA,ICC/IF。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Cathepsin Z Antibody (3J329) is a Rabbit antibody targeting Cathepsin Z. Anti-Cathepsin Z Antibody (3J329) can be used in ELISA,ICC/IF. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 3J329 |
| 交叉反应 | Mouse |
| 验证活性 | Immunofluorescence staining of mCTSZ in RAW264.7 cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-Mouse mCTSZ monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Cytoplasm. |
| 应用 | ELISA,ICC/IF |
| 推荐剂量 | ELISA: 1:5000-1:10000; ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CTSZ / CTSX / Cathepsin Z (rM CTSZ / CTSX / Cathepsin Z; TMPY-00736; NP_071720.1; Met 1-Val 306). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Cathepsin Z (CTSZ), also known as Cathepsin X or CATX, belongs to the C1 family of lysosomal cysteine proteases. Its gene structure and activity properties show several unique features that distinguish it clearly from other human cysteine proteases. It has a very short pro-region that shows no similarity to those of other cathepsins and a three-residue insertion motif that forms a characteristic ‘mini loop’. Cathepsin Z exhibits mono- and di-peptidase activity at its C-terminus, and in contrast to cathepsin B, it does not act as an endopeptidase. It is restricted to the cells of theimmune system, predominantly monocytes, macrophages and dendritic cells. Cathepsin Z is widely expressed in human tissues, suggesting that this enzyme could be involved in the normal intracellular protein degradation taking place in all cell types. It is capable to cleave regulatory motifs at C-terminus affecting the function of targeted molecules. Cathepsin X may regulate also the maturation of dendritic cells, a process, which is crucial in the initiation of adaptive immunity. Furthermore, higher levels of Cathepsin Z are also found in tumour and immune cells of prostate and gastric carcinomas and inmacrophages of gastric mucosa, especially after infection by Helicobacter pylori. Cathepsin Z is also ubiquitously distributed in cancer cell lines and in primary tumors from different sources, suggesting that this enzyme may participate in tumor progression. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse CTSZ / CTSX / Cathepsin Z protein (TMPY-00736) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-Cathepsin Z Antibody (3J329) | purchase Anti-Cathepsin Z Antibody (3J329) | Anti-Cathepsin Z Antibody (3J329) cost | order Anti-Cathepsin Z Antibody (3J329)
嗨！有任何问题？点我咨询
评论内容