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Anti-C1 inhibitor Antibody (4P478)
还可以产品编号 TMAY-01437
Anti-C1 inhibitor Antibody (4P478) 是一种 Mouse 抗体，靶向 C1 inhibitor。Anti-C1 inhibitor Antibody (4P478) 可用于 ELISA(Cap)。
Anti-C1 inhibitor Antibody (4P478)
Anti-C1 inhibitor Antibody (4P478)
还可以产品编号 TMAY-01437
Anti-C1 inhibitor Antibody (4P478) 是一种 Mouse 抗体，靶向 C1 inhibitor。Anti-C1 inhibitor Antibody (4P478) 可用于 ELISA(Cap)。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-C1 inhibitor Antibody (4P478) is a Mouse antibody targeting C1 inhibitor. Anti-C1 inhibitor Antibody (4P478) can be used in ELISA(Cap). |
| Ig Type | Monoclonal Mouse IgG2b |
| 克隆号 | 4P478 |
| 交叉反应 | Human |
| 应用 | ELISA(Cap) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human C1 inhibitor / SerpinG1 (rh C1 inhibitor / SerpinG1; TMPY-01183; NP_000053.2; Met1-Ala500). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact systems. By its C-terminal part (serpin domain), characterized by three beta-sheets and an exposed mobile reactive loop, C1-INH binds, and blocks the activity of its target proteases. The N-terminal end (nonserpin domain) confers to C1-INH the capacity to bind lipopolysaccharides and E-selectin. Owing to this moiety, C1-INH intervenes in regulation of the inflammatory reaction. The heterozygous deficiency of C1-INH results in hereditary angioedema (HAE). Owing to its ability to modulate the contact and complement systems and the convincing safety profile, plasma-derived C1 inhibitor is an attractive therapeutic protein to treat inflammatory diseases other than HAE. Deficiency of C1 inhibitor results in hereditary angioedema, which is characterized by recurrent episodes of localized angioedema of the skin, gastrointestinal mucosa or upper respiratory mucosa. C1 inhibitor may prove useful in a variety of other diseases including septic shock, reperfusion injury, hyperacute transplant rejection, traumatic and hemorrhagic shock, and the increased vascular permeability associated with thermal injury, interleukin-2 therapy and cardiopulmonary bypass. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human C1 inhibitor / SerpinG1 Protein (TMPY-01183) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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