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Anti-KNTC1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KNTC1。Anti-KNTC1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-KNTC1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KNTC1。Anti-KNTC1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-KNTC1 Polyclonal Antibody is a Rabbit antibody targeting KNTC1. Anti-KNTC1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat,Dog,Cow,Horse,Sheep) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Nucleus. Chromosome, centromere,kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Dynamic patternof localization during the cell cycle. At interphase, uniformlydistributed throughout the cytoplasm and nucleus. By prophase anduntil late stages of prometaphase, a fraction of the total pool isconcentrated at kinetochores. By metaphase, detected atkinetochores, along spindle fibers and most prominently at thepoles. By late anaphase until the end of telophase, no longerdetectable on kinetochores or along spindle fibers, but stillpresent at the spindle poles. |
| 组织特异性 | High expression in testis. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The kinetochore is the protein structure in eukaryotes which assembles on the centromere and links the chromosome to microtubule polymers from the mitotic spindle during mitosis and meiosis. The kinetochore contains two regions: an inner kinetochore, which is tightly associated with the centromere DNA; and an outer kinetochore, which interacts with microtubules. Even the simplest kinetochores consist of more than 45 different proteins, many of which are conserved throughout eukaryote species. |
| 免疫原 | KLH conjugated synthetic peptide: human KNTC1/Kinetochore |
| 抗原种属 | Human |
| 基因名称 | KNTC1 |
| 基因ID | |
| 蛋白名称 | Kinetochore-associated protein 1 |
| Uniprot ID | |
| 功能 | Essential component of the mitotic checkpoint, whichprevents cells from prematurely exiting mitosis. Required for theassembly of the dynein-dynactin and MAD1-MAD2 complexes ontokinetochores. |
| 分子量 | Theoretical: 251 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |