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别名 p-MYC (Thr58, Ser62), p-MYC (T58, S62), MYC (p-Thr58, Ser62), MYC (p-T58, S62)
Anti-Phospho-MYC (Thr58, 62) Antibody (3N813) 是一种 Rabbit 抗体,靶向 Phospho-MYC (Thr58, 62)。Anti-Phospho-MYC (Thr58, 62) Antibody (3N813) 可用于 WB,ICC/IF,IP。
Anti-Phospho-MYC (Thr58, 62) Antibody (3N813) 是一种 Rabbit 抗体,靶向 Phospho-MYC (Thr58, 62)。Anti-Phospho-MYC (Thr58, 62) Antibody (3N813) 可用于 WB,ICC/IF,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
| 产品描述 | Anti-Phospho-MYC (Thr58, 62) Antibody (3N813) is a Rabbit antibody targeting Phospho-MYC (Thr58, 62). Anti-Phospho-MYC (Thr58, 62) Antibody (3N813) can be used in ICC/IF,IP,WB. |
| 别名 | p-MYC (Thr58, Ser62), p-MYC (T58, S62), MYC (p-Thr58, Ser62), MYC (p-T58, S62) |
| Ig Type | IgG |
| 克隆号 | 3N813 |
| 交叉反应 | Human,Rat |
| 验证活性 | Western blot analysis of Phospho-c-Myc (T58+S62) on K562 cells lysates using anti-Phospho-c-Myc (T58+S62) antibody at 1/1,000 dilution. |
| 应用 | ICC/IFIPWB |
| 推荐剂量 | WB: 1:1000; ICC/IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | c-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease. Myc proteins are nuclear proteins with relatively short half lives. Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-Myc gene has been found amplified in neuroblastomas. The L-Myc gene has been reported to be amplified and expressed at high level in human small cell lung carcinomas. The presence of three sequence motifs in the c-Myc COOH terminus, including the leucine zipper, the helix-loop-helix and a basic region provided initial evidence for a sequence-specific binding function. A basic region helix-loop-helix leucine zipper motif (bHLH-Zip) protein, designated Max, specifically associates with c-Myc, N-Myc and L-Myc proteins. The Myc-Max complex binds to DNA in a sequence-specific manner under conditions where neither Max nor Myc exhibit appreciable binding. Max can also form heterodimers with at least two additional bHLH-Zip proteins, Mad and Mxi1, and Mad-Max dimers have been shown to repress transcription through interaction with mSin3. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Phospho |
| 免疫原 | A synthesized phosphopeptide: human c-Myc around the phosphorylation site of Thr58 and Ser62 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 49 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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