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Anti-Phospho-FKHR (Ser319) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-FKHR (Ser319)。Anti-Phospho-FKHR (Ser319) Polyclonal Antibody 可用于 WB,IHC,IF。
Anti-Phospho-FKHR (Ser319) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-FKHR (Ser319)。Anti-Phospho-FKHR (Ser319) Polyclonal Antibody 可用于 WB,IHC,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,230 | 5日内发货 |
产品描述 | Anti-Phospho-FKHR (Ser319) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FKHR (Ser319). Anti-Phospho-FKHR (Ser319) Polyclonal Antibody can be used in WB,IHC,IF. |
别名 | p-FKHR (Ser319), p-FKHR (S319), FKHR (p-Ser319), FKHR (p-S319) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of extracts from 3T3 cells untreated or treated with serum starvation using FKHR (Phospho-Ser319) Antibody TMAC-01494. 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using FKHR (Phospho-Ser319) Antibody TMAC-01494 (left) or the same antibody preincubated with blocking peptide (right). 3. Immunofluorescence staining of methanol-fixed Hela cells using FKHR (Phospho-Ser319) Antibody TMAC-01494. |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:100-300; IF: 1:50-200 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
性状 | Liquid |
缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
研究背景 | FKHR belongs to the forkhead family of transcription factors, which are characterized by a distinct forkhead domain. It may play a role in myogenic growth and differentiation. The mammalian DAF-16-like transcription factors, FKHR, FKHRL1, and AFX, function as key regulators of insulin signaling, cell cycle progression, and apoptosis downstream of phosphoinositide 3-kinase. Gene activation through binding to insulin response sequences has been essential for mediating these functions. D-type Cyclins (in Class III) is required for FKHR mediated inhibition of cell cycle progression and transformation. FKHR gene is mapped to chromosome 13q14 |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human FKHR around the phosphorylation site of Ser319 |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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