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Anti-Phospho-EGF Receptor (Tyr1045) Antibody (3A670)

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产品编号 TMAY-01619
别名 PIG61, NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB

Anti-Phospho-EGF Receptor (Tyr1045) Antibody (3A670) 是一种 Rabbit 抗体,靶向 Phospho-EGF Receptor (Tyr1045)。Anti-Phospho-EGF Receptor (Tyr1045) Antibody (3A670) 可用于 WB。

Anti-Phospho-EGF Receptor (Tyr1045) Antibody (3A670)

Anti-Phospho-EGF Receptor (Tyr1045) Antibody (3A670)

Rating icon 还可以
产品编号 TMAY-01619 别名 PIG61, NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB

Anti-Phospho-EGF Receptor (Tyr1045) Antibody (3A670) 是一种 Rabbit 抗体,靶向 Phospho-EGF Receptor (Tyr1045)。Anti-Phospho-EGF Receptor (Tyr1045) Antibody (3A670) 可用于 WB。

规格价格库存数量
20 μL
¥ 689
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100 μL
¥ 1,984
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产品介绍

生物活性
产品描述
Anti-Phospho-EGF Receptor (Tyr1045) Antibody (3A670) is a Rabbit antibody targeting Phospho-EGF Receptor (Tyr1045). Anti-Phospho-EGF Receptor (Tyr1045) Antibody (3A670) can be used in WB.
别名PIG61, NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB
Ig Type
Monoclonal Rabbit IgG
克隆号
3A670
交叉反应
Human
验证活性
Western blot analysis of extracts from serum-starved Hela, untreated (-) or treated with EGF (100 ng/mL, 10min) using Phospho-EGF Receptor (Tyr1045) rabbit monoclonal Antibody at 1:1000 dilution (upper) or anti-EGFR antibody (lower).
应用
WB
推荐剂量
WB: 1:1000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with a synthetic phosphopeptide corresponding to residues around Tyr1045 of the Human Phospho-EGF Receptor.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic phosphopeptide corresponding to residues around Tyr1045 of the Human Phospho-EGF Receptor
抗原种属
Human
研究领域
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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