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Anti-Phospho-EGF Receptor (Tyr1045) Antibody (3A670) 是一种 Rabbit 抗体,靶向 Phospho-EGF Receptor (Tyr1045)。Anti-Phospho-EGF Receptor (Tyr1045) Antibody (3A670) 可用于 WB。
Anti-Phospho-EGF Receptor (Tyr1045) Antibody (3A670) 是一种 Rabbit 抗体,靶向 Phospho-EGF Receptor (Tyr1045)。Anti-Phospho-EGF Receptor (Tyr1045) Antibody (3A670) 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
20 μL | ¥ 689 | 5日内发货 | |
100 μL | ¥ 1,984 | 5日内发货 |
产品描述 | Anti-Phospho-EGF Receptor (Tyr1045) Antibody (3A670) is a Rabbit antibody targeting Phospho-EGF Receptor (Tyr1045). Anti-Phospho-EGF Receptor (Tyr1045) Antibody (3A670) can be used in WB. |
别名 | PIG61, NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 3A670 |
交叉反应 | Human |
验证活性 | Western blot analysis of extracts from serum-starved Hela, untreated (-) or treated with EGF (100 ng/mL, 10min) using Phospho-EGF Receptor (Tyr1045) rabbit monoclonal Antibody at 1:1000 dilution (upper) or anti-EGFR antibody (lower). |
应用 | WB |
推荐剂量 | WB: 1:1000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with a synthetic phosphopeptide corresponding to residues around Tyr1045 of the Human Phospho-EGF Receptor. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
偶联 | Unconjugated |
免疫原 | A synthetic phosphopeptide corresponding to residues around Tyr1045 of the Human Phospho-EGF Receptor |
抗原种属 | Human |
研究领域 | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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