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Anti-JAM-A Antibody (9S605) 是一种 Mouse 抗体,靶向 JAM-A。Anti-JAM-A Antibody (9S605) 可用于 ELISA(Cap)。
Anti-JAM-A Antibody (9S605) 是一种 Mouse 抗体,靶向 JAM-A。Anti-JAM-A Antibody (9S605) 可用于 ELISA(Cap)。
产品描述 | Anti-JAM-A Antibody (9S605) is a Mouse antibody targeting JAM-A. Anti-JAM-A Antibody (9S605) can be used in ELISA(Cap). |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 9S605 |
交叉反应 | Human |
应用 | ELISA(Cap) |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Junctional Adhesion Molecule A (rh Junctional Adhesion Molecule A; TMPY-01035; NP_058642.1; Met1-Ala242). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0 |
研究背景 | Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer. |
偶联 | Unconjugated |
免疫原 | Recombinant Human Junctional Adhesion Molecule A Protein (TMPY-01035) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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