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Anti-SMPDL3A Antibody (9P822) 是一种 Rabbit 抗体,靶向 SMPDL3A。Anti-SMPDL3A Antibody (9P822) 可用于 ELISA。
Anti-SMPDL3A Antibody (9P822) 是一种 Rabbit 抗体,靶向 SMPDL3A。Anti-SMPDL3A Antibody (9P822) 可用于 ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 μL | ¥ 2,284 | 5日内发货 |
产品描述 | Anti-SMPDL3A Antibody (9P822) is a Rabbit antibody targeting SMPDL3A. Anti-SMPDL3A Antibody (9P822) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 9P822 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human SMPDL3A (rh SMPDL3A; TMPY-03278; Q92484; Met1-Tyr453). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | SMPDL3A gene is a novel liver X receptor (LXR) -regulated gene, with an LXR response element within its promoter. The induction of SMPDL3A is LXR-dependent and is restricted to human blood cells with no induction observed in mouse cellular systems. LXR α and LXRβ function as physiological sensors of cholesterol metabolites (oxysterols), regulating key genes involved in cholesterol and lipid metabolism. LXRs have been extensively studied in both human and rodent cell systems, revealing their potential therapeutic value in the contexts of atherosclerosis and inflammatory diseases. The LXR genome landscape has been investigated in murine macrophages but not in human THP-1 cells, which represent one of the frequently used monocyte/macrophage cell systems to study immune responses. |
偶联 | Unconjugated |
免疫原 | Recombinant Human SMPDL3A protein (TMPY-03278) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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