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Anti-ITGAV Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ITGAV。Anti-ITGAV Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP。
Anti-ITGAV Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ITGAV。Anti-ITGAV Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,170 | 5日内发货 | |
100 μL | ¥ 1,965 | 5日内发货 | |
200 μL | ¥ 2,795 | 5日内发货 |
产品描述 | Anti-ITGAV Polyclonal Antibody is a Rabbit antibody targeting ITGAV. Anti-ITGAV Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP. |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Paraformaldehyde-fixed, paraffin embedded Human Invasive urothelial carcinoma; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Integrin Alpha V Polyclonal Antibody, Unconjugated (TMAB-00994) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded Human Placenta; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Integrin Alpha V Polyclonal Antibody, Unconjugated (TMAB-00994) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded Human Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Integrin Alpha V Polyclonal Antibody, Unconjugated (TMAB-00994) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 4. 25 μg total protein per Lane of various lysates probed with Integrin Alpha V polyclonal antibody, unconjugated (TMAB-00994) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min. |
应用 | |
推荐剂量 | WB: 1:500-1:2000; IHC-P: 1:100-1:500; IHC-Fr: 1:100-1:500; ICC/IF: 1:50-1:200; IF: 1:100-1:500; IP: 1:20-1:50 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Cell Membrane |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metatastatic diffusion of tumour cells. ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; ITGB1, ITGB3, ITGB5, ITGB6, and ITGB8), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. |
免疫原 | KLH conjugated synthetic peptide: human Integrin Alpha V |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Integrins,Integrins,Platelets,Host Virus Interaction,T Lymphocytic Lineage |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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