Anti-ITGAV Polyclonal Antibody is a Rabbit antibody targeting ITGAV. Anti-ITGAV Polyclonal Antibody can be used in ICC/IF,IF,IHC-Fr,IHC-P,IP,WB.

IgG

Human,Mouse,Rat

1. Paraformaldehyde-fixed, paraffin embedded Human Invasive urothelial carcinoma; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Integrin Alpha V Polyclonal Antibody, Unconjugated (TMAB-00994) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded Human Placenta; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Integrin Alpha V Polyclonal Antibody, Unconjugated (TMAB-00994) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Human Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Integrin Alpha V Polyclonal Antibody, Unconjugated (TMAB-00994) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
4. 25 μg total protein per Lane of various lysates probed with Integrin Alpha V polyclonal antibody, unconjugated (TMAB-00994) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.

WB: 1:500-1:2000; IHC-P: 1:100-1:500; IHC-Fr: 1:100-1:500; ICC/IF: 1:50-1:200; IF: 1:100-1:500; IP: 1:20-1:50

Polyclonal

KLH conjugated synthetic peptide: human Integrin Alpha V

Human

ITGAV

Integrin alpha-V

Integrins,Integrins,Platelets,Host Virus Interaction,T Lymphocytic Lineage

The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.