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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-HAO1 Antibody (8R666)

Synonyms: hydroxyacid oxidase (glycolate oxidase) 1, HAOX1, GOX1, GOX
货号 TMAY-02222 一键复制产品信息
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202603开学季活动

Anti-HAO1 Antibody (8R666) 是一种 Rabbit 抗体，靶向 HAO1。Anti-HAO1 Antibody (8R666) 可用于 ELISA。

Anti-HAO1 Antibody (8R666)

一键复制产品信息
Rating icon 还可以
202603开学季活动
货号 TMAY-02222

别名 hydroxyacid oxidase (glycolate oxidase) 1, HAOX1, GOX1, GOX

Anti-HAO1 Antibody (8R666) 是一种 Rabbit 抗体，靶向 HAO1。Anti-HAO1 Antibody (8R666) 可用于 ELISA。

Anti-HAO1 Antibody (8R666)
规格价格库存数量
100 μL
¥ 2,284
5日内发货
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产品介绍

生物活性
产品描述
Anti-HAO1 Antibody (8R666) is a Rabbit antibody targeting HAO1. Anti-HAO1 Antibody (8R666) can be used in ELISA.
别名
hydroxyacid oxidase (glycolate oxidase) 1, HAOX1, GOX1, GOX
Ig Type
Rabbit IgG
克隆号
8R666
反应种属
Human
特异性
Human HAO1
应用ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human HAO1 (rh HAO1; TMPY-01770; NP_060015.1; Leu 2-Ile 370).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Hydroxyacid oxidase 1, also known as Glycolate oxidase, HAO1, and GOX1, is a member of the FMN-dependent alpha-hydroxy acid dehydrogenase family. HAO1 / GOX1 has 2-hydroxyacid oxidase activity. It is most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate. HAO1 / GOX1 is a liver-specific peroxisomal enzyme that oxidizes glycolate to glyoxylate with the concomitant production of H2O2. In Hao1 messenger RNA (mRNA), an iron-responsive element (IRE) homologous to the sequence recognized by iron regulatory proteins (IRP), key regulators of iron homeostasis, is present. Mammalian HAO1 / GOX1 is a peroxisomal protein and that the C-terminal sequence SKI acts as the targeting signal. Down-regulation of HAO1 / GOX1 expression during oxidative stress may provide a mechanism to prevent excessive H2O2 formation in liver peroxisomes and may represent the prototype of a poorly recognized but potentially relevant response to an oxidative injury involving down-regulation of ROS-producing enzymes.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human HAO1 / GOX1 protein (TMPY-01770)
抗原种属
Human
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器

关键词

HAOX-1HAOX 1GOX-1GOX 1
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