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Anti-SOX-2 Antibody (7C478)
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产品编号 TMAY-00056
Anti-SOX-2 Antibody (7C478) 是一种 Rabbit 抗体，靶向 SOX-2。Anti-SOX-2 Antibody (7C478) 可用于 IHC-P。
Anti-SOX-2 Antibody (7C478)
331 Anti-SOX-2 Antibody (7C478)
还可以产品编号 TMAY-00056
Anti-SOX-2 Antibody (7C478) 是一种 Rabbit 抗体，靶向 SOX-2。Anti-SOX-2 Antibody (7C478) 可用于 IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,289 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-SOX-2 Antibody (7C478) is a Rabbit antibody targeting SOX-2. Anti-SOX-2 Antibody (7C478) can be used in IHC-P. |
| Ig Type | Rabbit IgG |
| 克隆号 | 7C478 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human SOX2 in human testis with rabbit monoclonal antibody (1:300, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human SOX2 in human brain with rabbit monoclonal antibody (1:300, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:100-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the N-terminus of the human Sox2. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | SOX2 is a member of the SOXB1 subfamily of transcription factors most notably involved in the reprogramming of somatic cells into induced pluripotent stem cells. Housed on chromosome 3, the SOX2 gene encodes for a protein with a C-terminal transcriptional activation domain and a DNA-binding HMG domain that contains a nuclear localization/export signal. SOX2 forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development and pluripotency such as YES1, FGF4, UTF1 and ZFP206. Mutations in this gene have been associated with bilateral eye disease. SOX2 antigen and antibody were found in small-cell lung cancer cell lines and sera. However, neither exists in normal sera, suggesting that SOX2 might be a potential tumor target or marker. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: N-terminus of the human Sox2. |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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