Anti-TXN Antibody (7Z328)

Name: Anti-TXN Antibody (7Z328)
Brand: TargetMol
SKU: TMAY-03478
Rating: 4.5 (1 reviews)

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产品编号 TMAY-03478

Anti-TXN Antibody (7Z328) 是一种 Rabbit 抗体，靶向 TXN。Anti-TXN Antibody (7Z328) 可用于 WB,ELISA。

Anti-TXN Antibody (7Z328)

还可以

产品编号 TMAY-03478

Anti-TXN Antibody (7Z328) 是一种 Rabbit 抗体，靶向 TXN。Anti-TXN Antibody (7Z328) 可用于 WB,ELISA。

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生物活性

产品描述	Anti-TXN Antibody (7Z328) is a Rabbit antibody targeting TXN. Anti-TXN Antibody (7Z328) can be used in WB,ELISA.
Ig Type	Monoclonal Rabbit IgG
克隆号	7Z328
交叉反应	Mouse
验证活性	Anti-Txn rabbit monoclonal antibody at 1:500 dilution. -Lane A: Hela Whole Cell Lysate. -Lane B: A431 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:27 kDa. -Observed band size:27 kDa
应用	WB,ELISA
推荐剂量	WB: 1:500-1:1000; ELISA: 1:25000-1:50000
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Thioredoxin/TXN/SASP (rM Thioredoxin/TXN/SASP; TMPY-00382; P10639; Met1-Val105).
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	Thioredoxin, also known as ATL-derived factor, Surface-associated sulphydryl protein, SASP and TXN, is a nucleus, cytoplasm and secreted protein that belongs to the thioredoxin family. Thioredoxins are proteins that act as antioxidants by facilitating the reduction of other proteins by cysteine thiol-disulfide exchange. Thioredoxins are found in nearly all known organisms and are essential for life in mammals. Thioredoxin / TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Thioredoxin / TXN plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Thioredoxin / TXN nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Thioredoxin / TXN induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Mouse Thioredoxin/TXN/SASP Protein (TMPY-00382)
抗原种属	Mouse

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.