购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GARNL1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06335

Anti-GARNL1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GARNL1。Anti-GARNL1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-GARNL1 Polyclonal Antibody

Anti-GARNL1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06335

Anti-GARNL1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GARNL1。Anti-GARNL1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-GARNL1 Polyclonal Antibody is a Rabbit antibody targeting GARNL1. Anti-GARNL1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic and Nuclear. Translocated to the nucleus when associated with TCF3/E12.
组织特异性Widely expressed.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景GARNL1 is expressed during embryogenesis with E12. During development, GARNL1 expression decreases, persisting at high levels only in neurons of the adult brain. GARNL1 localizes to the cytoplasm where it may play a role regulating GTP hydrolysis of proteins such as Ran and Rap. GARNL1 is imported to the nucleus via dimerization with E12. GARNL1 interacts with the HLH region of E12 and may function to negatively regulate the transcription of E12-dependent downstream target genes. This suggests that at least a portion of the function of GARNL1 is dependent upon its association with E12. GARNL1 may also associate with other HLH proteins and influence a variety of HLH signaling cascades. In adult brain, GARNL1 activity does not involve E12 and therefore it may serve a different function in developed neural tissue.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GARNL1
抗原种属
Human
基因名称
RALGAPA1
基因ID
253959
蛋白名称
Ral GTPase-activating protein subunit alpha-1
Uniprot ID
Q6GYQ0
功能
GTPase activating Rap/RanGAP domain-like 1 (GARNL1) is an interacting partner of the transcription factor TCF3/isoform E12, mainly in the developing embryonic forebrain. It may be an important transcriptional regulator of downstream target genes under the control of TCF3/E12, by disrupting HLH dimer formation of TCF3/E12 with other proteins and may be involved in neuronal differentiation.
化学信息
分子量Theoretical: 230 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-GARNL1 Polyclonal Antibody | purchase Anti-GARNL1 Polyclonal Antibody | Anti-GARNL1 Polyclonal Antibody cost | order Anti-GARNL1 Polyclonal Antibody | Anti-GARNL1 Polyclonal Antibody molecular weight