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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MICA Antibody (1U567)

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货号 TMAB-08808

Anti-MICA Antibody (1U567) 是一种 Rabbit 抗体，靶向 MICA。Anti-MICA Antibody (1U567) 可用于 WB。

Anti-MICA Antibody (1U567)

Anti-MICA Antibody (1U567)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08808

Anti-MICA Antibody (1U567) 是一种 Rabbit 抗体，靶向 MICA。Anti-MICA Antibody (1U567) 可用于 WB。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-MICA Antibody (1U567) is a Rabbit antibody targeting MICA. Anti-MICA Antibody (1U567) can be used in WB.
Ig Type
IgG
克隆号
1U567
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Cytoplasm. Expressed on the cell surface in gastric epithelium, endothelial cells and fibroblasts and in the cytoplasm in keratinocytes and monocytes. Infection with human adenovirus 5 suppresses cell surface expression due to the adenoviral E3-19K protein which causes retention in the endoplasmic reticulum.
组织特异性Widely expressed with the exception of the central nervous system where it is absent. Expressed predominantly in gastric epithelium and also in monocytes, keratinocytes, endothelial cells, fibroblasts and in the outer layer of Hassal's corpuscles within the medulla of normal thymus. In skin, expressed mainly in the keratin layers, basal cells, ducts and follicles. Also expressed in many, but not all, epithelial tumors of lung, breast, kidney, ovary, prostate and colon. In thyomas, overexpressed in cortical and medullar epithelial cells. Tumors expressing MICA display increased levels of gamma delta T cells.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
抗原信息
免疫原
A synthesized peptide: human MIC A
抗原种属
Human
基因名称
MICA
基因ID
100507436
蛋白名称
MHC class I chain-related protein A
Uniprot ID
Q29983
功能
Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
化学信息
分子量Theoretical: 43 kDa. Actual: 42-70 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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