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Anti-CD43 Antibody (5M635)

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货号 TMAB-03988

Anti-CD43 Antibody (5M635) 是一种 Rabbit 抗体，靶向 CD43。Anti-CD43 Antibody (5M635) 可用于 WB,FCM。

Anti-CD43 Antibody (5M635)

Anti-CD43 Antibody (5M635)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03988

Anti-CD43 Antibody (5M635) 是一种 Rabbit 抗体，靶向 CD43。Anti-CD43 Antibody (5M635) 可用于 WB,FCM。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD43 Antibody (5M635) is a Rabbit antibody targeting CD43. Anti-CD43 Antibody (5M635) can be used in WB,FCM.
Ig Type
IgG
克隆号
5M635
反应种属
Human
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度0.5mg/ml
研究背景This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]
抗原信息
基因名称
SPN
基因ID
6693
蛋白名称
Leukosialin
功能
One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1. During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.
化学信息
分子量Theoretical: 38 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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