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Anti-APOE Antibody (3H64)

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货号 TMAB-02765

Anti-APOE Antibody (3H64) 是一种 Mouse 抗体,靶向 APOE。Anti-APOE Antibody (3H64) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-APOE Antibody (3H64)

Anti-APOE Antibody (3H64)

一键复制产品信息
Rating icon 还可以
货号 TMAB-02765

Anti-APOE Antibody (3H64) 是一种 Mouse 抗体,靶向 APOE。Anti-APOE Antibody (3H64) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-APOE Antibody (3H64) is a Mouse antibody targeting APOE. Anti-APOE Antibody (3H64) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG1, Kappa
克隆号
3H64
反应种属
Human,Mouse
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-100; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Secreted.
组织特异性Occurs in all lipoprotein fractions in plasma. It constitutes 10-20% of very low density lipoproteins (VLDL) and 1-2% of high density lipoproteins (HDL). APOE is produced in most organs. Significant quantities are produced in liver, brain, spleen, lung, adrenal, ovary, kidney and muscle.
构建方式Recombinant Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. Defects in ApoE are a cause of hyperlipoproteinemia type III due to increased plasma cholesterol and triglycerides levels which are the consequence of impaired clearance of chylomicron and VLDL remnants.
抗原信息
基因名称
APOE
基因ID
蛋白名称
Apolipoprotein E
功能
Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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