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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GLS2 Polyclonal Antibody

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货号 TMAB-06523

Anti-GLS2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GLS2。Anti-GLS2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-GLS2 Polyclonal Antibody

Anti-GLS2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06523

Anti-GLS2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GLS2。Anti-GLS2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-GLS2 Polyclonal Antibody is a Rabbit antibody targeting GLS2. Anti-GLS2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion.
组织特异性Highly expressed in liver. Expressed in brain and pancreas. Not observed in heart, placenta, lung, skeletal muscle and kidney. Expression is significantly reduced in hepatocellular carcinomas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景LGA is a 602 amino acid protein that localizes to the mitochondrion and contains two ANK repeats. Expressed in brain, liver and pancreas, LGA functions as a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. LGA is overexpressed in breast cancer cell lines, suggesting a role for LGA in tumorigenesis. The gene encoding LGA maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GLS2/LGA
抗原种属
Human
基因名称
GLS2
基因ID
27165
蛋白名称
Glutaminase liver isoform, mitochondrial
Uniprot ID
Q9UI32
功能
Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.
化学信息
分子量Theoretical: 65 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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