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Anti-FDPS Antibody-FITC (8F434)
还可以产品编号 TMAY-02550F
Anti-FDPS Antibody-FITC (8F434) 是一种 FITC-conjugated Rabbit 抗体，靶向 FDPS。Anti-FDPS Antibody-FITC (8F434) 可用于 FCM。
Anti-FDPS Antibody-FITC (8F434)
Anti-FDPS Antibody-FITC (8F434)
还可以产品编号 TMAY-02550F
Anti-FDPS Antibody-FITC (8F434) 是一种 FITC-conjugated Rabbit 抗体，靶向 FDPS。Anti-FDPS Antibody-FITC (8F434) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-FDPS Antibody-FITC (8F434) is a FITC-conjugated Rabbit antibody targeting FDPS. Anti-FDPS Antibody-FITC (8F434) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8F434 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human FDPS expression on HeLa cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and then stained with FITC-conjugated anti-Human FDPS. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human FDPS (rh FDPS; TMPY-02654; NP_001129294.1; Met1-Lys353) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | Z-farnesyl diphosphate synthase (FDPS) is an enzyme belonging to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. Z-farnesyl diphosphate synthase (FDPS) functions as key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate, a precurcor for several classes of essential metabolites. FDPS catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Functions of FDPS may be inactivated by interferon-induced RSAD2. This inactivation may result of disruption of lipid rafts at the plasma membrane, and thus have an antiviral effect since many enveloped viruses need lipid rafts to bud efficiently out of the cell. |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human FDPS protein (TMPY-02654) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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