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顶部生物活性储存和溶解信息计算器

Anti-HDAC6 Antibody (7M972)

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Anti-HDAC6 Antibody (7M972)
产品编号 TMAC-01784

Anti-HDAC6 Antibody (7M972) 是一种 Rabbit 抗体，靶向 HDAC6。Anti-HDAC6 Antibody (7M972) 可用于 WB,ICC/IF,IHC,IP。

Anti-HDAC6 Antibody (7M972)

Anti-HDAC6 Antibody (7M972)

Rating icon 还可以
Anti-HDAC6 Antibody (7M972)
产品编号 TMAC-01784

Anti-HDAC6 Antibody (7M972) 是一种 Rabbit 抗体，靶向 HDAC6。Anti-HDAC6 Antibody (7M972) 可用于 WB,ICC/IF,IHC,IP。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-HDAC6 Antibody (7M972) is a Rabbit antibody targeting HDAC6. Anti-HDAC6 Antibody (7M972) can be used in WB,ICC/IF,IHC,IP.
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of HDAC6 on Jurkat cells lysates using anti-HDAC6 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-HDAC6 antibody. Counter stained with hematoxylin.
3. ICC staining HDAC6 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining HDAC6 in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining HDAC6 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC/IF
IHC
IP
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBPassociated factor), p300/CBP, HAT1, and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3-6, have been identified as histone deacetylases.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q9UBN7
化学信息
分子量Theoretical: 131 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

Tubulin-lysine deacetylase HDAC6Protein deacetylase HDAC6KIAA-0901KIAA0901Histone deacetylase 6HDAC6HDAC 6HD6HD 6

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