Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Macimorelin (EP-1572) acetate,一种 GH 促分泌素,是一种具有口服活性的GHSR 激动剂。Macimorelin acetate 可刺激 GH 的释放。Macimorelin acetate 可用于成人生长激素缺乏症 (AGHD) 和癌症厌食-恶病质综合征 (CACS) 的研究。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
25 mg | ¥ 13,900 | 8-10周 | ||
50 mg | ¥ 18,300 | 8-10周 | ||
100 mg | ¥ 23,500 | 8-10周 |
产品描述 | Macimorelin Acetate (EP-1572), an orally active growth hormone (GH) secretagogue and a ghrelin receptor (GHSR) agonist, stimulates GH release. It is utilized in research focusing on adult growth hormone deficiency (AGHD) and Cancer Anorexia-Cachexia Syndrome (CACS). |
体外活性 |
NFATc1-IN-1 (0、0.5、1.0、1.5、2.0、2.5 μM, 4 days) exhibits potent inhibitory activities on osteoclast formation and function, which eventually translates into decreased bone resorption while showing no cytotoxic effects towards osteoclast precursor cells at concentrations of as high as 2.5 μM.[1] NFATc1-IN-1 (1.5-2.5 μM, 24 h) blocks NFATc1 nuclear translocation and decreases the level of NFATc1.[1] |
别名 | EP-1572 acetate ; AEZS-130 acetate, AEZS-130 acetate, EP-1572 acetate |
分子量 | 534.61 |
分子式 | C28H34N6O5 |
CAS No. | 945212-59-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Macimorelin acetate 945212-59-9 EP-1572 acetate ; AEZS-130 acetate D-87575 acetate Macimorelin EP-1572 Acetate EP-1572 EP-1572 acetate ; AEZS 130 Acetate EP-1572 acetate ; AEZS-130 Acetate EP 1572 Macrilen JMV 1843 AEZS-130 acetate UMV-1843 AEZS130 Acetate EP 1572 Acetate AEZS 130 EP1572 AibDTrpDgTrpCHO. Macimorelin Acetate UMV1843 Macimorelin Acetate AEZS130 AEZS-130 Acetate UMV 1843 JMV1843 ARD07 EP1572 Acetate AEZS-130 EP-1572 acetate ARD-07 EP-1572 acetate ; AEZS130 Acetate JMV-1843 AEZS 130 Acetate Inhibitor inhibitor inhibit