Name: CD300A Protein, Human, Recombinant (hFc & His)
Brand: TargetMol
SKU: TMPJ-00187
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 456

6-8日内发货

10 μg

¥ 740

6-8日内发货

20 μg

¥ 1,120

5日内发货

50 μg

¥ 1,970

5日内发货

100 μg

¥ 3,380

5日内发货

200 μg

¥ 5,850

5日内发货

500 μg

¥ 12,100

5日内发货

1 mg

¥ 17,300

5日内发货

生物活性

产品描述	CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD300b, CD300e) and inhibitory members (CD300a, CD300f), as well as molecules presenting a negative charge within their transmembrane domain (CD300c, CD300d). It is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. CD300c is a functional immune receptor able to deliver activating signals upon ligation in RBL-2H3 mast cells.
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD300b, CD300e) and inhibitory members (CD300a, CD300f), as well as molecules presenting a negative charge within their transmembrane domain (CD300c, CD300d). It is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. CD300c is a functional immune receptor able to deliver activating signals upon ligation in RBL-2H3 mast cells.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc-6xHis
蛋白编号	Q9UGN4
氨基酸序列	Leu18-Gln178
蛋白构建	Leu18-Gln178
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 150 mM NaCl, 5% Trehalose, pH 8.0.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	NK inhibitory receptor, IRC1/IRC2, Inhibitory receptor protein 60, Immunoglobulin superfamily member 12, CMRF35-like molecule 8, CMRF-35-H9, CMRF35-H, CD300 antigen-like family member A
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.

化学信息

分子量	60-75 KDa (reducing condition)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

CD300A Protein, Human, Recombinant (hFc & His)

CD300A Protein, Human, Recombinant (hFc & His)

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