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4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc)

4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc)

产品编号 TMPJ-00141
别名: 4-1BB ligand receptor, CD137, CDw137, ILA, TNFRSF9, T-cell antigen 4-1BB homolog, T-cell antigen ILA

4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60 KDa and the accession number is A9YYE7.

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4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc)
规格 价格/CNY 货期 数量
10 μg ¥ 580 5日内发货
50 μg ¥ 1,370 5日内发货
500 μg ¥ 6,640 5日内发货
1 mg ¥ 9,490 5日内发货
夏季3重特惠
药物设计专题培训
Chloroquine限时半价
产品目录号及名称: 4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc) (TMPJ-00141)
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生物活性
技术参数
产品性质
生物活性 Loaded Human 4-1BBL-His on HIS1K Biosensor, can bind Cynomolgus 4-1BB-Fc with an affinity constant of <10-3 nM as determined in BLI assay. (Regularly tested)
产品描述 4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60 KDa and the accession number is A9YYE7.
种属 Cynomolgus
表达系统 HEK293 Cells
标签 C-hFc
蛋白编号 A9YYE7
别名 4-1BB ligand receptor, CD137, CDw137, ILA, TNFRSF9, T-cell antigen 4-1BB homolog, T-cell antigen ILA
氨基酸序列 Leu24-Gln186
蛋白构建 Leu24-Gln186
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 60 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Tumor necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surface protein belonging to the tumor necrosis factor receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. CD137 is expressed by mesenchymal cells, including endothelial cells, chondrocytes, and cells of the central nervous system. CD137 is also broadly expressed by cells of the human immune system, is broadly expressed by cells of the human immune system, including activated CD8+ and CD4+ T cells, activated natural killer (NK) cells, follicular dendritic cells (FDCs) and monocytes. CD137 has diverse roles in the immune response, the one key function is to promote the survival of both T cells and dendritic cells by binding the cognate ligand CD137L (4-1BBL).

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Keywords

4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc) CD 137 4-1BB ligand receptor CD137 CDw137 ILA TNFRSF-9 TNFRSF9 TNFRSF 9 T-cell antigen 4-1BB homolog T-cell antigen ILA CD-137 recombinant recombinant-proteins proteins protein

 

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