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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ELMO3 Polyclonal Antibody

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货号 TMAB-05541

Anti-ELMO3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ELMO3。Anti-ELMO3 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-ELMO3 Polyclonal Antibody

Anti-ELMO3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05541

Anti-ELMO3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ELMO3。Anti-ELMO3 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-ELMO3 Polyclonal Antibody is a Rabbit antibody targeting ELMO3. Anti-ELMO3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Pig,Cow,Horse,GuineaPig)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Elmo1 associates with DOCK 180 and may influence phagocytosis and effect cell shape changes. Src family kinase mediated tyrosine phosphorylation of ELMO1 influences signaling through Elmo1/Crk/DOCK 180 pathways. Elmo2 interacts directly with Rho G in a GTP-dependent manner and forms a ternary complex with DOCK 180 to induce activation of Rac 1. The RhoG-Elmo2-DOCK 180 pathway is required for activation of Rac 1 and cell spreading mediated by integrin, as well as for neurite outgrowth induced by nerve growth factor. Elmo3 acts in assocation with DOCK180 and Crk II and may be required in complex with DOCK180 to activate Rac/Rho small GTPases.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ELMO3
抗原种属
Human
基因名称
ELMO3
基因ID
79767
蛋白名称
Engulfment and cell motility protein 3
Uniprot ID
Q96BJ8
功能
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
化学信息
分子量Theoretical: 69 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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