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Anti-IDE Antibody (5U690) 是一种 Rabbit 抗体,靶向 IDE。Anti-IDE Antibody (5U690) 可用于 WB,IHC。
Anti-IDE Antibody (5U690) 是一种 Rabbit 抗体,靶向 IDE。Anti-IDE Antibody (5U690) 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-IDE Antibody (5U690) is a Rabbit antibody targeting IDE. Anti-IDE Antibody (5U690) can be used in WB,IHC. |
别名 | Insulysin, Insulin-Degrading Enzyme, Insulinase, Insulin Protease, IDE, Aβ-Degrading Protease, Abeta-Degrading Protease |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat,zebrafish |
验证活性 | 1. Western blot analysis of Insulin degrading enzyme on different lysates using anti-Insulin degrading enzyme antibody at 1/1,000 dilution. Positive control: Lane 1: zebrafish, Lane 2: Hela, Lane 3: K562. 2. Western blot analysis of Insulin degrading enzyme on hybrid fish (crucian-carp) heart tissue lysate using anti-Insulin degrading enzyme antibody at 1/500 dilution. 3. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Insulin degrading enzyme antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-Insulin degrading enzyme antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human gastric carcinoma tissue using anti-Insulin degrading enzyme antibody. Counter stained with hematoxylin. 6. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-Insulin degrading enzyme antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Insulin degrading enzyme (IDE), also known as insulinase, insulin protease or insulysin, cleaves the peptide hormone insulin with consequences for insulin response and resistance. IDE is a highly conserved thiol metalloprotease with ubiquitous expression including the brain. Since its discovery, IDE has been shown to degrade a variety of bioactive peptides. Recently the finding that IDE clears intracellular and extracellular amyloid products has spurred research into the link between IDE function and human neurodegenerative disease such as Alzheimer??s. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 118 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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