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Anti-SUN2 Antibody (2Y616)

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Anti-SUN2 Antibody (2Y616)
产品编号 TMAC-03917
别名 UNC84B, unc84, C. elegans, homolog of, B, unc84 homolog B (C. elegans), unc84 homolog B, UNC 84B, SUN domain-containing protein 2, SUN 2, Sad1/unc-84 protein-like 2, Sad1/unc84 protein-like, Sad1 unc-84 domain protein 2, Sad1 unc84 domain protein, Sad1 and UNC84 domain containing 2, RAB5IP, Rab5 interacting protein, Protein unc-84 homolog B, nuclear envelope protein, KIAA0668, FRIGG

Anti-SUN2 Antibody (2Y616) 是一种 Rabbit 抗体,靶向 SUN2。Anti-SUN2 Antibody (2Y616) 可用于 WB,IHC,FCM,ICC,IF。

Anti-SUN2 Antibody (2Y616)

Anti-SUN2 Antibody (2Y616)

Rating icon 还可以
Anti-SUN2 Antibody (2Y616)
产品编号 TMAC-03917 别名 UNC84B, unc84, C. elegans, homolog of, B, unc84 homolog B (C. elegans), unc84 homolog B, UNC 84B, SUN domain-containing protein 2, SUN 2, Sad1/unc-84 protein-like 2, Sad1/unc84 protein-like, Sad1 unc-84 domain protein 2, Sad1 unc84 domain protein, Sad1 and UNC84 domain containing 2, RAB5IP, Rab5 interacting protein, Protein unc-84 homolog B, nuclear envelope protein, KIAA0668, FRIGG

Anti-SUN2 Antibody (2Y616) 是一种 Rabbit 抗体,靶向 SUN2。Anti-SUN2 Antibody (2Y616) 可用于 WB,IHC,FCM,ICC,IF。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-SUN2 Antibody (2Y616) is a Rabbit antibody targeting SUN2. Anti-SUN2 Antibody (2Y616) can be used in WB,IHC,FCM,ICC,IF.
别名UNC84B, unc84, C. elegans, homolog of, B, unc84 homolog B (C. elegans), unc84 homolog B, UNC 84B, SUN domain-containing protein 2, SUN 2, Sad1/unc-84 protein-like 2, Sad1/unc84 protein-like, Sad1 unc-84 domain protein 2, Sad1 unc84 domain protein, Sad1 and UNC84 domain containing 2, RAB5IP, Rab5 interacting protein, Protein unc-84 homolog B, nuclear envelope protein, KIAA0668, FRIGG
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of SUN2 on rat kidney tissue lysate using anti-SUN2 antibody at 1/2,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-SUN2 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-SUN2 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-SUN2 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using anti-SUN2 antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-SUN2 antibody. Counter stained with hematoxylin.
7. ICC staining SUN2 (green) in SK-Br-3 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. Flow cytometric analysis of SK-Br-3 cells with SUN2 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
应用
推荐剂量
WB: 1:500-2000; IHC: 1:50-200; ICC:IF: 1:50-100; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景SUN2 (sad1/unc-84 protein-like 2), also known as UNC84B (unc-84 homolog B), FRIGG, KIAA0668 or RAB5IP, is a 717 amino acid single-pass membrane protein that contains one SUN domain and localizes to the membrane of both the nucleus and the endosome. Widely expressed in a variety of tissues, including lung, muscle and heart, SUN2 interacts with Rab 5A and may play a role in homotypic endosome fusion. The gene encoding SUN2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.
偶联与修饰
偶联
Unconjugated
抗原信息
Uniprot ID
化学信息
分子量Theoretical: 80 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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