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顶部生物活性储存和溶解信息计算器

Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944)

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产品编号 TMAH-00943

别名 p-PPP2CA (Y307), p-PPP2CA (Tyr307), PPP2CA (p-Y307), PPP2CA (p-Tyr307), Phospho-PPP2CA (Y307)

Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) 是一种抗体，靶向 Phospho-PPP2CA (Tyr307)。Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) 可用于 ELISA,WB。

Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944)

Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944)

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产品编号 TMAH-00943 别名 p-PPP2CA (Y307), p-PPP2CA (Tyr307), PPP2CA (p-Y307), PPP2CA (p-Tyr307), Phospho-PPP2CA (Y307)

Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) 是一种抗体，靶向 Phospho-PPP2CA (Tyr307)。Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) 可用于 ELISA,WB。

规格价格库存数量
50 μL
¥ 1,310
5日内发货
100 μL
¥ 2,190
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) is an antibody targeting Phospho-PPP2CA (Tyr307). Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) can be used in ELISA,WB.
别名p-PPP2CA (Y307), p-PPP2CA (Tyr307), PPP2CA (p-Y307), PPP2CA (p-Tyr307), Phospho-PPP2CA (Y307)
Ig Type
Rabbit IgG
克隆号
7S944
交叉反应
Human
验证活性
Western Blot
-Positive WB detected in A549 whole cell lysate(treated with EGF or not)
-All lanes Phospho-PPP2CA antibody at 0.95μg/ml
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 35 KDa
-Observed band size: 35 KDa
应用ELISAWB
推荐剂量
WB:1:500-1:5000.
抗体种类
Monoclonal
亚细胞定位Cytoplasm. Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle pole.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'. Mediates dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint. Mediates dephosphorylation of MYC; promoting its ubiquitin-mediated proteolysis: interaction with AMBRA1 enhances interaction between PPP2CA and MYC. Mediates dephosphorylation of FOXO3; promoting its stabilization: interaction with AMBRA1 enhances interaction between PPP2CA and FOXO3.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human Phospho-PPP2CA (Y307)
抗原种属
Human
基因名称
PPP2CA
基因ID
5515
Uniprot ID
P67775
研究领域
Signal Transduction
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

Serine/threonine-protein phosphatase 2A catalytic subunit α isoformSerine/threonine-protein phosphatase 2A catalytic subunit alpha isoformSerine/threonine-protein phosphatase 2A catalytic subunit a isoformRP-CRPCReplication protein C (RP-C)pPPP2CA (Y307)pPPP2CA (Tyr307)PPP2CA (pY307)PPP2CA (pTyr307)PPP2CA (phospho-Y307)PPP2CA (phospho-Tyr307)PPP2CAPP2A-αPP2AαPP2A-alphaPP2A-a

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