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Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944)

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产品编号 TMAH-00943
别名 Phospho-PPP2CA (Y307)

Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) 是一种抗体,靶向 Phospho-PPP2CA (Tyr307)。Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) 可用于 ELISA, WB。

Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944)

Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944)

Rating icon 还可以
产品编号 TMAH-00943 别名 Phospho-PPP2CA (Y307)

Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) 是一种抗体,靶向 Phospho-PPP2CA (Tyr307)。Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) 可用于 ELISA, WB。

规格价格库存数量
50 μL
¥ 1,310
5日内发货
100 μL
¥ 2,190
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) is an antibody targeting Phospho-PPP2CA (Tyr307). Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) can be used in ELISA, WB.
别名Phospho-PPP2CA (Y307)
Ig Type
Rabbit IgG
克隆号
7S944
交叉反应
Human
验证活性
Western Blot
-Positive WB detected in A549 whole cell lysate(treated with EGF or not)
-All lanes Phospho-PPP2CA antibody at 0.95μg/ml
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 35 KDa
-Observed band size: 35 KDa
应用
ELISA, WB
推荐剂量
WB:1:500-1:5000.
抗体种类
Monoclonal
亚细胞定位Cytoplasm. Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle pole.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'. Mediates dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint. Mediates dephosphorylation of MYC; promoting its ubiquitin-mediated proteolysis: interaction with AMBRA1 enhances interaction between PPP2CA and MYC. Mediates dephosphorylation of FOXO3; promoting its stabilization: interaction with AMBRA1 enhances interaction between PPP2CA and FOXO3.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human Phospho-PPP2CA (Y307)
抗原种属
Human
基因ID
5515
Uniprot ID
研究领域
Signal Transduction
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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