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顶部生物活性储存和溶解信息计算器

Anti-VCAM1 Monoclonal Antibody-Biotin

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产品编号 TMAZ-0012B

别名 Vascular cell adhesion protein 1, INCAM-100

Anti-VCAM1 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting VCAM1. Anti-VCAM1 Monoclonal Antibody-Biotin can be used in ELISA, FCM. 可用于 ELISA,FCM。

Anti-VCAM1 Monoclonal Antibody-Biotin

Anti-VCAM1 Monoclonal Antibody-Biotin

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产品编号 TMAZ-0012B 别名 Vascular cell adhesion protein 1, INCAM-100

Anti-VCAM1 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting VCAM1. Anti-VCAM1 Monoclonal Antibody-Biotin can be used in ELISA, FCM. 可用于 ELISA,FCM。

规格价格库存数量
25 μg
¥ 1,250
7日内发货
50 μg
¥ 1,500
7日内发货
100 μg
¥ 2,099
7日内发货
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产品介绍

生物活性
产品描述
Anti-VCAM1 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting VCAM1. Anti-VCAM1 Monoclonal Antibody-Biotin can be used in ELISA,FCM.
别名Vascular cell adhesion protein 1, INCAM-100
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of VCAM1 overexpressed 400F cells with TMAZ-0012B, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用ELISAFCM
推荐剂量
0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Single-pass type I membrane
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of VCAM1 protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in PBS.
纯度> 95% as determined by SDS-PAGE.
研究背景Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation (PubMed: 31310649). Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins (PubMed: 10209034). During inflammatory responses, binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration (PubMed: 22970700). Serves also as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation (PubMed: 35210567)
偶联与修饰
偶联
Biotin
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
VCAM1
抗原种属
Human
基因ID
7412
Uniprot ID
P19320
研究领域
Immunology Research
化学信息
分子量150 kDa
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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