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Anti-BCL10 Antibody (4H852)
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产品编号 TMAC-00388
别名 Mammalian CARD-containing adapter molecule E10 (mE10), CLAP, CIPER, Cellular-E10 (c-E10), Cellular homolog of vCARMEN (cCARMEN), CED-3/ICH-1 prodomain homologous E10-like regulator (CIPER), CARD-like apoptotic protein (hCLAP), CARD-containing molecule enhancing NF-kappa-B, Bcl10, B-cell lymphoma/leukemia 10, B-cell CLL/lymphoma 10 (Bcl-10)
Anti-BCL10 Antibody (4H852) 是一种 Rabbit 抗体，靶向 BCL10。Anti-BCL10 Antibody (4H852) 可用于 WB,ICC/IF,IHC,IP。
Anti-BCL10 Antibody (4H852)
Anti-BCL10 Antibody (4H852)
还可以产品编号 TMAC-00388 别名 Mammalian CARD-containing adapter molecule E10 (mE10), CLAP, CIPER, Cellular-E10 (c-E10), Cellular homolog of vCARMEN (cCARMEN), CED-3/ICH-1 prodomain homologous E10-like regulator (CIPER), CARD-like apoptotic protein (hCLAP), CARD-containing molecule enhancing NF-kappa-B, Bcl10, B-cell lymphoma/leukemia 10, B-cell CLL/lymphoma 10 (Bcl-10)
Anti-BCL10 Antibody (4H852) 是一种 Rabbit 抗体，靶向 BCL10。Anti-BCL10 Antibody (4H852) 可用于 WB,ICC/IF,IHC,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
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偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-BCL10 Antibody (4H852) is a Rabbit antibody targeting BCL10. Anti-BCL10 Antibody (4H852) can be used in WB,ICC/IF,IHC,IP. |
| 别名 | Mammalian CARD-containing adapter molecule E10 (mE10), CLAP, CIPER, Cellular-E10 (c-E10), Cellular homolog of vCARMEN (cCARMEN), CED-3/ICH-1 prodomain homologous E10-like regulator (CIPER), CARD-like apoptotic protein (hCLAP), CARD-containing molecule enhancing NF-kappa-B, Bcl10, B-cell lymphoma/leukemia 10, B-cell CLL/lymphoma 10 (Bcl-10) |
| Ig Type | IgG |
| 交叉反应 | Human |
| 应用 | |
| 推荐剂量 | WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Bcl10, also designated CIPER, c-CARMEN and mE10, was first identified as a gene truncated or mutated in MALT B cell lymphomas and other tumor types. Bcl10 is homologous to the equine herpesvirus-2 E10 gene and, like E10, it contains an N-terminal caspase recruitment domain (CARD). Expression of Bcl10 has been shown to induce NFκB activation in a NIK-dependent pathway, and research indicates that the CARD domain is essential for this activation; although in a separate study, Bcl10 by itself did not induce JNK or NFκB activation. Overexpression of Bcl10 has been shown to induce apoptosis in a manner dependent on CARD-mediated oligomerization. Bcl10 has also been shown to play a role in processing of caspase-9 to its active dimer. Other studies have shown that Bcl10 is not mutated in many human tumors and lymphomas. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 31 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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