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Anti-AGR2 Antibody (7E227)

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Anti-AGR2 Antibody (7E227)
产品编号 TMAC-00099
别名 Secreted Cement Gland Protein XAG-2 Homolog, HPC8, hAG-2, Anterior Gradient Protein 2 Homolog, AGR2, AG-2, AG2

Anti-AGR2 Antibody (7E227) 是一种 Rabbit 抗体,靶向 AGR2。Anti-AGR2 Antibody (7E227) 可用于 WB,ICC,IHC,IP,FCM。

Anti-AGR2 Antibody (7E227)

Anti-AGR2 Antibody (7E227)

Rating icon 还可以
Anti-AGR2 Antibody (7E227)
产品编号 TMAC-00099 别名 Secreted Cement Gland Protein XAG-2 Homolog, HPC8, hAG-2, Anterior Gradient Protein 2 Homolog, AGR2, AG-2, AG2

Anti-AGR2 Antibody (7E227) 是一种 Rabbit 抗体,靶向 AGR2。Anti-AGR2 Antibody (7E227) 可用于 WB,ICC,IHC,IP,FCM。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-AGR2 Antibody (7E227) is a Rabbit antibody targeting AGR2. Anti-AGR2 Antibody (7E227) can be used in WB,ICC,IHC,IP,FCM.
别名Secreted Cement Gland Protein XAG-2 Homolog, HPC8, hAG-2, Anterior Gradient Protein 2 Homolog, AGR2, AG-2, AG2
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of AGR2 on MCF-7 cells lysates using anti-AGR2 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-AGR2 antibody. Counter stained with hematoxylin.
3. ICC staining AGR2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining AGR2 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining AGR2 in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. Flow cytometric analysis of Hela cells with AGR2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200; ICC: 1:100-500; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景AGR2 (Anterior Gradient Protein 2), also known as AG2, GOB-4 or HAG-2, is a member of the anterior gradient homolog family. It is the human ortholog of XAG-2, the secreted Xenopus laevis Anterior Gradient protein. In X. laevis, it is involved in cement gland differentiation and neural marker gene expression. AGR2 is a secretory protein encoded by two different AGR2 transcripts. It interacts with LYPD3 and α-dystroglycan (DAG-1). AGR2 is ubiquitously expressed with up-regulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR). AGR2 may serve as a potential therapeutic marker for various cancers.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 17 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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