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Anti-TGFBR3 Antibody (1I111)

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产品编号 TMAY-03351
别名 βglycan, transforming growth factor, β receptor III, transforming growth factor, beta receptor III, BGCAN, betaglycan

Anti-TGFBR3 Antibody (1I111) 是一种 Rabbit 抗体,靶向 TGFBR3。Anti-TGFBR3 Antibody (1I111) 可用于 ELISA。

Anti-TGFBR3 Antibody (1I111)

Anti-TGFBR3 Antibody (1I111)

Rating icon 还可以
产品编号 TMAY-03351 别名 βglycan, transforming growth factor, β receptor III, transforming growth factor, beta receptor III, BGCAN, betaglycan

Anti-TGFBR3 Antibody (1I111) 是一种 Rabbit 抗体,靶向 TGFBR3。Anti-TGFBR3 Antibody (1I111) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,294
5日内发货
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产品介绍

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产品描述
Anti-TGFBR3 Antibody (1I111) is a Rabbit antibody targeting TGFBR3. Anti-TGFBR3 Antibody (1I111) can be used in ELISA.
别名βglycan, transforming growth factor, β receptor III, transforming growth factor, beta receptor III, BGCAN, betaglycan
Ig Type
Monoclonal Rabbit IgG
克隆号
1I111
交叉反应
Mouse
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TGFBR3 (rM TGFBR3; TMPY-02224; NP_035708.2; Met1-Arg399).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Betaglycan also known as transforming growth factor beta receptor III (TGFBR3), is a cell-surface chondroitin sulfate / heparan sulfate proteoglycan. TGFBR3 is a transforming growth factor (TGF)-beta type III receptor. This receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. TGFBR3 is the TGF-β component most commonly downregulated among localized human prostate cancer studies. TGFBR3 knockdown led to focus formation and enhanced expression of CD133, a marker found on prostate cancer stem cells. TGFBR3 is an accessory receptor that binds to and modulates the activities of both transforming growth factor-beta (TGFβ) and inhibin, two members of the TGFβ superfamily of growth factors that regulate many aspects of reproductive biology. TGFBR3 is known to be expressed in adult testis and ovary, but little is known about this receptor during gonadogenesis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Mouse TGFBR3 protein (TMPY-02224)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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