购物车
- 全部删除
- 您的购物车当前为空
Anti-TGFBR3 Antibody (1I111) 是一种 Rabbit 抗体,靶向 TGFBR3。Anti-TGFBR3 Antibody (1I111) 可用于 ELISA。
Anti-TGFBR3 Antibody (1I111) 是一种 Rabbit 抗体,靶向 TGFBR3。Anti-TGFBR3 Antibody (1I111) 可用于 ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 μL | ¥ 2,294 | 5日内发货 |
产品描述 | Anti-TGFBR3 Antibody (1I111) is a Rabbit antibody targeting TGFBR3. Anti-TGFBR3 Antibody (1I111) can be used in ELISA. |
别名 | βglycan, transforming growth factor, β receptor III, transforming growth factor, beta receptor III, BGCAN, betaglycan |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 1I111 |
交叉反应 | Mouse |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TGFBR3 (rM TGFBR3; TMPY-02224; NP_035708.2; Met1-Arg399). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Betaglycan also known as transforming growth factor beta receptor III (TGFBR3), is a cell-surface chondroitin sulfate / heparan sulfate proteoglycan. TGFBR3 is a transforming growth factor (TGF)-beta type III receptor. This receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. TGFBR3 is the TGF-β component most commonly downregulated among localized human prostate cancer studies. TGFBR3 knockdown led to focus formation and enhanced expression of CD133, a marker found on prostate cancer stem cells. TGFBR3 is an accessory receptor that binds to and modulates the activities of both transforming growth factor-beta (TGFβ) and inhibin, two members of the TGFβ superfamily of growth factors that regulate many aspects of reproductive biology. TGFBR3 is known to be expressed in adult testis and ovary, but little is known about this receptor during gonadogenesis. |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse TGFBR3 protein (TMPY-02224) |
抗原种属 | Mouse |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
评论内容