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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-NPC1 Monoclonal Antibody (4B880)

Synonyms: NPC
货号 TMAT-0560 一键复制产品信息
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Anti-NPC1 Monoclonal Antibody (4B880) 是一种 Mouse 抗体，靶向 NPC1。Anti-NPC1 Monoclonal Antibody (4B880) 可用于 IHC,FCM。

Anti-NPC1 Monoclonal Antibody (4B880)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0560

别名 NPC

Anti-NPC1 Monoclonal Antibody (4B880) 是一种 Mouse 抗体，靶向 NPC1。Anti-NPC1 Monoclonal Antibody (4B880) 可用于 IHC,FCM。

Anti-NPC1 Monoclonal Antibody (4B880)
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产品介绍

生物活性
产品描述
Anti-NPC1 Monoclonal Antibody (4B880) is a Mouse antibody targeting NPC1. Anti-NPC1 Monoclonal Antibody (4B880) can be used in IHC,FCM.
别名
NPC
Ig Type
IgG1
克隆号
4B880
反应种属
Human
应用IHCFCM
推荐剂量
IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human NPC1 (AA: 34-174) expressed in E. Coli.
抗原种属
Human
基因名称
NPC1
基因ID
4864
蛋白名称
NPC intracellular cholesterol transporter 1
Uniprot ID
O15118
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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