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Anti-KRT13 Antibody (2C427) 是一种 Rabbit 抗体,靶向 KRT13。Anti-KRT13 Antibody (2C427) 可用于 WB,ICC,IHC。
Anti-KRT13 Antibody (2C427) 是一种 Rabbit 抗体,靶向 KRT13。Anti-KRT13 Antibody (2C427) 可用于 WB,ICC,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-KRT13 Antibody (2C427) is a Rabbit antibody targeting KRT13. Anti-KRT13 Antibody (2C427) can be used in WB,ICC,IHC. |
别名 | WSN2, Type I keratin Ka13, type I cytoskeletal 13, MGC3781, MGC161462, Krt1-13, Krt-1.13, KRT 13, Keratin-13, keratin type I cytoskeletal 13, Keratin 13, Keratin, Ka13, K1C13_HUMAN, K13, Cytokeratin-13, Cytokeratin 13, CK-13, CK13, 47 kDa cytokeratin |
Ig Type | IgG |
交叉反应 | Human,Mouse,zebrafish |
验证活性 | 1. Western blot analysis of Cytokeratin 13 on human lung lysates using anti-Cytokeratin 13 antibody at 1/1,000 dilution. 2. Western blot analysis of Cytokeratin 13 hybrid fish (crucian-carp) brain tissue lysate using anti-Cytokeratin 13 antibody at 1/500 dilution. 3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cytokeratin 13 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-Cytokeratin 13 antibody. Counter stained with hematoxylin. 5. ICC staining Cytokeratin 13 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. ICC staining Cytokeratin 13 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining Cytokeratin 13 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
应用 | |
推荐剂量 | WB: 1:1000-5000; IHC: 1:50-200; ICC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation, which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 13 belongs to the intermediate filament family and is a heterotetramer of two type I acidic and two type II basic keratins. It is generally associated with cytokeratin 4. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder which predominantly affects noncornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 50 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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